SGLT-2 inhibition and glucagon: Cause for alarm?
SGLT-2 inhibition and glucagon: Cause for alarm?
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DOI:
10.1016/j.tem.2015.05.011
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发表时间:
2015-07
期刊:
影响因子:
--
通讯作者:
Kibbey RG
中科院分区:
文献类型:
--
作者:
Kibbey RG
Recent studies raised the alarm that the inhibition of sodium-coupled glucose transporter type 2 in humans increases endogenous glucose production rates by an unclear mechanism. Surprisingly, a potential explanation may be linked directly to the alpha-cell. Is this a mechanistic spoiler or an added benefit?