Towards a Repository for Standardized Medical Image and Signal Case Data Annotated with Ground Truth
Towards a Repository for Standardized Medical Image and Signal Case Data Annotated with Ground Truth
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DOI：
10.1007/s10278-011-9428-4
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发表时间：
2012-04-01
影响因子：
4.4
通讯作者：
Horsch, Alexander
中科院分区：
文献类型：
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作者：
Deserno, Thomas M.;Welter, Petra;Horsch, Alexander
医疗信号和图像处理系统的验证需要质量有保证的、具有代表性的和普遍认可的数据库，并附有适当的参考（地面实况）和临床元数据，这些数据是为每个项目精心编写的，不与科学界共享。在我们的设想中，这些数据将集中存储在一个开放的存储库中。我们提出了一个标准化的案例数据和地面实况信息存储库的架构，支持计算机辅助诊断的评估和分析，该架构基于（a）NASA空间数据系统咨询委员会提供的开放式档案信息系统（OAIS）参考模型（ISO 14721：2003），（B）都柏林核心元数据倡议（DCMI）元素集（ISO 15836：2009），（c）开放档案倡议（OAI）元数据采集协议，以及（d）医学应用图像检索（IRMA）框架。在我们的实现中，门户将数据提交和检索所需的所有功能集中在一起。管理数据的完整生命周期（定义、创建、存储、维护、共享、使用和改进）。复杂的搜索工具使数据集的使用更加容易，这些数据集可能来自不同的提供商。完整的历史记录保证了可重复性。用永久数字对象标识符生成标准化创建报告。此创建报告必须由所有数据用户引用。这些报告的同行评审电子出版将为数据贡献者创造声誉，并将形成关于图像和信号数据集的事实标准。验证方法的良好实践指南补充了案例库的概念。该程序将增加医学信号和图像处理方法和应用的评价研究的可比性。
Validation of medical signal and image processing systems requires quality-assured, representative and generally acknowledged databases accompanied by appropriate reference (ground truth) and clinical metadata, which are composed laboriously for each project and are not shared with the scientific community. In our vision, such data will be stored centrally in an open repository. We propose an architecture for a standardized case data and ground truth information repository supporting the evaluation and analysis of computer-aided diagnosis based on (a) the Reference Model for an Open Archival Information System (OAIS) provided by the NASA Consultative Committee for Space Data Systems (ISO 14721:2003), (b) the Dublin Core Metadata Initiative (DCMI) Element Set (ISO 15836:2009), (c) the Open Archive Initiative (OAI) Protocol for Metadata Harvesting, and (d) the Image Retrieval in Medical Applications (IRMA) framework. In our implementation, a portal bunches all of the functionalities that are needed for data submission and retrieval. The complete life cycle of the data (define, create, store, sustain, share, use, and improve) is managed. Sophisticated search tools make it easier to use the datasets, which may be merged from different providers. An integrated history record guarantees reproducibility. A standardized creation report is generated with a permanent digital object identifier. This creation report must be referenced by all of the data users. Peer-reviewed e-publishing of these reports will create a reputation for the data contributors and will form de-facto standards regarding image and signal datasets. Good practice guidelines for validation methodology complement the concept of the case repository. This procedure will increase the comparability of evaluation studies for medical signal and image processing methods and applications.