Evaluation of corneal hysteresis and corneal resistance factor after corneal cross-linking for keratoconus
Evaluation of corneal hysteresis and corneal resistance factor after corneal cross-linking for keratoconus
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DOI：
10.1007/s00417-011-1897-0
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发表时间：
2012-04-01
影响因子：
2.7
通讯作者：
Kozobolis, Vassilios
中科院分区：
文献类型：
--
作者：
Gkika, Maria;Labiris, Georgios;Kozobolis, Vassilios
目的观察圆锥角膜（KC）患者角膜胶原交联（CXL）前后角膜滞后（CH）和角膜阻力因子（CRF）的变化。此外，为了确定与一系列角膜和人口统计学因素的潜在相关性，该研究包括50只接受CXL的KC眼。用眼反应分析仪（ORA）测定CH和CRF。尝试与裸眼视力（UVA）、最佳矫正视力（BSCVA）、中央角膜厚度（CCT）、平均角膜曲率（Km）、散光（Astig.）残余散光、年龄和性别。非KC眼的CH和CRF（平均值+/- SD）分别为10.1 +/- 1.9 mmHg和9.7 +/- 2.4 mmHg，而KC眼术前分别为8.2 +/- 1.4 mmHg（p = 0.007）和7.4 +/- 2.3 mmHg（p = 0.01）。KC眼术前和术后CH和CRF测量值之间无显著差异（分别为p = 0.518和p = 0.479）。ORA参数与BSCVA、CCT、Km、Astig呈显著相关。ORA参数在KC和非KC眼之间显示出显著差异。CH和CRF均与视力和角膜参数显著相关。CXL对ORA测量值无显著影响。
To evaluate corneal hysteresis (CH) and corneal resistance factor (CRF) in keratoconic (KC) eyes before and after corneal collagen cross-linking (CXL). Furthermore, to determine potential correlations with a series of corneal and demographic factors.The study consisted of 50 KC eyes that underwent CXL. CH and CRF were measured by the ocular response analyzer (ORA). Correlations were attempted with uncorrected visual acuity (UVA), best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), mean keratometry (Km), astigmatism (Astig.), residual astigmatism, age, and gender. Fifty non-KC eyes served as controls.CH and CRF (mean +/- SD) for non-KC eyes were 10.1 +/- 1.9 mmHg and 9.7 +/- 2.4 mmHg respectively, while for KC eyes preoperatively they were 8.2 +/- 1.4 mmHg (p = 0.007) and 7.4 +/- 2.3 mmHg (p = 0.01) respectively. Non-significant differences were detected between preoperative and postoperative CH and CRF measurements in KC eyes (p = 0.518 and p = 0.479 respectively). Significant correlations were found between ORA parameters and BSCVA, CCT, Km, Astig. and residual astigmatism.ORA parameters demonstrate significant differences between KC and non-KC eyes. Both CH and CRF present significant correlations with visual acuity and corneal parameters. CXL exerts a non-significant impact on ORA measurements.