Morphology and mechanical property of quenched poly(L-lactide)/N,N-dimethylacetamide gels
Morphology and mechanical property of quenched poly(L-lactide)/N,N-dimethylacetamide gels
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DOI：
10.1016/j.polymer.2022.124581
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发表时间：
2022-02-01
期刊：
影响因子：
4.6
通讯作者：
Hotta, Atsushi
中科院分区：
文献类型：
--
作者：
Inukai, Shunya;Kurokawa, Naruki;Hotta, Atsushi
采用液氮快速淬冷法合成了具有机械坚韧的聚L-乳酸（PLLA）/N，N-二甲基乙酰胺（DMAc）凝胶。将110 ° C下的PLLA/DMAc溶液在室温下冷却（PLLA-RT），或在保持在RT下之前通过LN淬灭（PLLA-LN）。PLLA浓度为5wt%、8wt%和11wt%的PLLA-RT不形成凝胶，而PLLA浓度为14wt%和17wt%的PLLA-RT可以形成显示粗糙结构的脆性凝胶。而PLLA-LN则可以形成稳定的凝胶，与PLLA浓度无关。在0.1%的应变下，PLLA浓度为17wt%的凝胶的储能模量从78.7kPa（PLLA-RT）增加到563.7kPa（PLLA-LN）。从结构分析，PLLA-RT形成球晶（直径100-200 μ m），而PLLA-LN形成相对均匀的网络结构，具有连续的微孔骨架，没有球晶。结构的变化显着有助于形成稳定的，可重塑的，可生物降解的，和生物相容性的物理凝胶与生态友好和增强的机械性能。
Mechanically tough poly(L-lactide) (PLLA)/N,N-dimethylacetamide (DMAc) gels by rapid quenching using liquid nitrogen (LN) were synthesized. PLLA/DMAc solution at 110 degrees C was cooled at room temperature (PLLA-RT), or quenched by LN before keeping at RT (PLLA-LN). PLLA-RT with the PLLA concentrations of 5, 8, and 11 wt% did not form gel, while PLLA-RT with 14 and 17 wt% could form brittle gel exhibiting coarse structures. In contrast, PLLA-LN could form stable gel regardless of the PLLA concentration. The storage modulus of the gel with the PLLA concentration of 17 wt% increased from 78.7 kPa (PLLA-RT) to 563.7 kPa (PLLA-LN) at the strain of 0.1%. From the structural analysis, PLLA-RT formed spherulites (100-200 mu m in diameter), whereas PLLA-LN formed relatively uniform network structures with continuous microporous skeletons without spherulites. The structural changes significantly contributed to the formation of stable, re-moldable, biodegradable, and biocompatible physical gels with ecofriendly and enhanced mechanical properties.