The prevalence and characteristics of suicidality in HIV/AIDS as seen in an African population in Entebbe district, Uganda
The prevalence and characteristics of suicidality in HIV/AIDS as seen in an African population in Entebbe district, Uganda
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DOI：
10.1186/1471-244x-12-63
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发表时间：
2012-06-18
期刊：
影响因子：
4.4
通讯作者：
Patel, Vikram
中科院分区：
文献类型：
--
作者：
Kinyanda, Eugene;Hoskins, Susan;Patel, Vikram
背景：HIV/AIDS患者的自杀倾向不仅是未来自杀未遂和完全自杀的预测因子，而且与生活质量差和抗逆转录病毒治疗的依从性差有关。本文调查了非洲国家乌干达艾滋病毒/艾滋病的自杀率及其相关性。方法：对在乌干达半城市的两家艾滋病毒诊所就诊的618名受访者进行了横断面研究。使用结构化问卷收集有关人口、社会、心理和临床因素的数据。结果：中高度自杀风险(MHS)发生率为7.8%，终生自杀未遂发生率为3.9%。在单因素分析中，与MHS相关的因素有：女性、食物不安全、负性生活事件增多、高应激分数、消极应对方式、既往精神病史、心理社会障碍、创伤后应激障碍、广泛性焦虑障碍和严重抑郁障碍的诊断。在多变量模型中，女性、不断增加的负性生活事件、既往精神病史和严重抑郁障碍与MHS独立相关。结论：这些结果与社会和心理应激源作用于潜在素质(包括既往和现在的精神疾病)导致自杀的模型是一致的。这些结果确定了通过治疗精神疾病和促进更好地适应艾滋病毒/艾滋病患者的生活来降低风险的潜在目标。
Background: Suicidality in HIV/AIDS is not only a predictor of future attempted suicide and completed suicide, it is also associated with poor quality of life and poor adherence with antiretroviral therapy. This paper examines the prevalence and correlates of suicidality in HIV/AIDS in the African nation of Uganda.Methods: A cross-sectional study was undertaken among 618 respondents attending two HIV clinics in semi-urban Uganda. A structured questionnaire was used to collect data on demographic, social, psychological and clinical factors. Correlates of suicidality were assessed using mulitvariable logistic regression.Results: Prevalence of 'moderate to high risk for suicidality' (MHS) was 7.8 % and that of life-time attempted suicide was 3.9 %. Factors associated with MHS at univariate analysis were: female gender, food insecurity, increasing negative life events, high stress score, negative coping style, past psychiatric history, psychosocial impairment, diagnoses of post-traumatic stress disorder, generalised anxiety disorder and major depressive disorder. Factors independently associated with MHS in multivariate models were female gender, increasing negative life events, a previous psychiatric history, and major depressive disorder.Conclusions: These results are in agreement with the stress-vulnerability model where social and psychological stressors acting on an underlying diathesis (including previous and current psychiatric morbidities) leads to suicidality. These results identify potential targets to mitigate risk through treatment of psychiatric disorders and promoting greater adaptation to living with HIV/AIDS.