Outdoor light at night, overweight, and obesity in school-aged children and adolescents
Outdoor light at night, overweight, and obesity in school-aged children and adolescents
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夜间室外光与学龄儿童和青少年超重和肥胖
DOI：
10.1016/j.envpol.2022.119306
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发表时间：
2022-04-16
影响因子：
8.9
通讯作者：
Hu, Li-Wen
中科院分区：
文献类型：
--
作者：
Lin, Li-Zi;Zeng, Xiao-Wen;Hu, Li-Wen
以前的研究表明，夜间户外光线（LAN）与成年人超重或肥胖的患病率较高有关。然而，LAN水平与儿童超重或肥胖的关系仍然未知。这项研究利用了东北七城市研究的数据，其中包括47，990名学龄儿童和青少年（6-18岁）。使用卫星成像数据测量室外局域网水平。根据世界卫生组织（WHO）生长标准，使用体重和身高计算年龄性别特异性体重指数（BMI）Z评分。超重和肥胖的定义采用中国标准。通过问卷调查获得有关社会经济状况、睡眠相关特征和致肥胖因素的信息。广义线性混合模型研究了室外LAN水平（四分位数）与感兴趣的结果的关联。与户外LAN水平最低四分之一的儿童相比，暴露于较高户外LAN水平的儿童的BMI Z评分更大，超重的几率更高（包括肥胖）或肥胖，最大估计值在第三四分位数[BMI Z评分：β = 0.26，95% CI：0.18-0.33;超重（包括肥胖）：OR = 1.40，95%CI：1.25-1.56;肥胖：OR = 1.46，95%CI：1.29-1.65]。户外LAN水平与BMI Z分数的相关性存在显著的性别差异（P-交互作用< 0.001），男性的相关性更强。在进行多项敏感性分析和调整睡眠相关特征、致肥胖因素和环境暴露后，结果仍然稳健。我们的研究结果表明，较高的户外LAN水平与较大的BMI Z分数以及学龄儿童和青少年超重（包括肥胖）和肥胖的可能性有关。此外，户外LAN水平和BMI Z分数之间的关联在男性中更强。未来的研究与暴露评估，同时考虑室外和室内局域网的曝光是必要的。
Previous studies have indicated that outdoor light at night (LAN) is associated with a higher prevalence of overweight or obesity in adults. However, the association of LAN levels with overweight or obesity in children is still unknown. This study utilized data from the Seven Northeastern Cities study, which included 47,990 school aged children and adolescents (ages 6-18 years). Outdoor LAN levels were measured using satellite imaging data. Weight and height were used to calculate age-sex-specific body mass index (BMI) Z-scores based on the World Health Organization (WHO) growth standards. Overweight status and obesity were defined using the Chinese standard. Information regarding socioeconomic status, sleep-related characteristics, and obesogenic factors were obtained using a questionnaire. A generalized linear mixed model examined the associations of outdoor LAN levels (in quartiles) with the outcomes of interest. Compared to children in the lowest quartile of outdoor LAN levels, children exposed to higher outdoor LAN levels had larger BMI Z-scores and higher odds of being overweight (including obesity) or obese, with the largest estimates in the third quartile [BMI Z-score: beta = 0.26, 95% CI: 0.18-0.33; overweight (including obesity): OR = 1.40, 95% CI: 1.25-1.56; obesity: OR = 1.46, 95% CI: 1.29-1.65]. There was a significant sex difference (P-interaction < 0.001) in the association of outdoor LAN levels with BMI Z-scores, and the association was stronger in males. Results remained robust following multiple sensitivity analyses and the adjustment of sleep-related characteristics, obesogenic factors, and environmental exposures. Our findings suggest that higher outdoor LAN levels are associated with larger BMI Z-scores and greater odds of overweight (including obesity) and obesity in school-aged children and adolescents. Further, the association between outdoor LAN levels and BMI Z-scores is stronger in males. Future studies with exposure assessments that consider both outdoor and indoor LAN exposures are needed.