PREVALENCE OF ANTICIPATORY NAUSEA AND OTHER SIDE-EFFECTS IN CANCER-PATIENTS RECEIVING CHEMOTHERAPY
PREVALENCE OF ANTICIPATORY NAUSEA AND OTHER SIDE-EFFECTS IN CANCER-PATIENTS RECEIVING CHEMOTHERAPY
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DOI：
10.1016/s0959-8049(05)80427-7
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发表时间：
1993-01-01
影响因子：
8.4
通讯作者：
TATTERSALL, MHN
中科院分区：
文献类型：
--
作者：
BOAKES, RA;TARRIER, N;TATTERSALL, MHN
对98名接受化疗的癌症患者进行了访谈，以确定预期恶心和呕吐，焦虑和饮食变化的患病率。在接受过至少4次治疗的患者中，41%的人报告至少有轻度预期恶心（AN）。对于24%的人来说，这是一个中度到重度的问题，这与对治疗的高度焦虑显着相关。该水平的患病率与受试者是否作为住院或门诊患者接受治疗无关。仅12例患者报告了预期性呕吐（AV），其中11例为女性;这是样本中发现的唯一性别效应。中度AN和AV之间的独立性也由触发效应的事件类型的差异提出：AN主要是气味和AV治疗的想法。接受至少四次治疗的患者中，50%报告了开始化疗后饮食的变化。最常见的表现形式是对肉类的厌恶，然后是对咖啡的厌恶，最常见的原因是味觉的变化，然后是食欲不振。
98 patients receiving chemotherapy for cancer were interviewed to determine the prevalence of anticipatory nausea and vomiting, anxiety and dietary changes. Among those who had received at least four treatments 41% reported at least mild anticipatory nausea (AN). For 24% this was a moderate to severe problem, which was significantly associated with a high level of anxiety about treatment. Prevalence at this level was independent of whether the subject was receiving treatment as an in- or an outpatient. Anticipatory vomiting (AV) was reported by only 12 patients, of whom 11 were women; this was the only effect of gender found in the sample. Independence between moderate AN and AV was also suggested by a difference in type of event triggering the effect: predominantly odours for AN and thoughts of the treatment for AV. Changes in diet after commencing chemotherapy were reported by 50% of patients who had received at least four treatments. These most commonly took the form of aversions to meat and then to coffee, and were attributed most frequently to changes in taste and then to loss of appetite.