High-resolution ultrasound biomicroscopy for monitoring ovarian structures in mice

High-resolution ultrasound biomicroscopy for monitoring ovarian structures in mice
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DOI:
10.1186/1477-7827-7-69
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发表时间:
2009-07-06
影响因子:
4.4
通讯作者:
Adams, Gregg P.
Adams, Gregg P.
中科院分区:
医学2区
文献类型:
--
作者:
Jaiswal, Rajesh S.;Singh, Jaswant;Adams, Gregg P.

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背景:直到最近,超声系统空间分辨率的限制阻碍了以波状方式发展的 20 微米结构的表征。结论:小鼠是使用经皮超声生物显微镜研究卵巢动力学的合适模型。反复全身麻醉检查对动情周期没有明显影响,初步结果显示小鼠卵泡发育呈波浪状。
Background: Until recently, the limit of spatial resolution of ultrasound systems has prevented characterization of structures = 20 microns develop in a wavelike fashion.Conclusion: The mouse is a suitable model for the study of ovarian dynamics using transcutaneous ultrasound bio-microscopy. Repeated general anesthesia for examination had no apparent effect on the estrous cycle, and preliminary results revealed a wave-like pattern of ovarian follicle development in mice.