Characterization and identification of exflagellation-inducing factor in the salivary gland of Anopheles stephensi (Diptera: Culicidae)
Characterization and identification of exflagellation-inducing factor in the salivary gland of Anopheles stephensi (Diptera: Culicidae)
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DOI：
10.1006/bbrc.2001.5675
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发表时间：
2001-10-05
影响因子：
3.1
通讯作者：
Matsuoka, H
中科院分区：
文献类型：
--
作者：
Hirai, M;Wang, JC;Matsuoka, H
配子激活因子（GAF）诱导疟原虫小配子脱落。我们在雌蚊斯氏按蚊的唾液腺中发现了GAF。在唾液腺粗匀浆上清液中以浓度依赖的方式诱导鞭毛。唾液腺的促排活性高于中肠和头部。唾液腺中的GAF具有热稳定性和低分子量(
Gamete activation factor (GAF) induces exflagellation of Plasmodium microgametes. We found GAF in the salivary glands of female mosquitoes, Anopheles stephensi. The exflagellation was induced in a concentration-dependent manner in the supernatant of salivary gland's crude homogenate. The exflagellation-inducing activity in the salivary gland was higher than that in the midgut and the head. GAF in the salivary glands was found to be heat stable and low molecular weight (