X-ray photoemission studies of the interaction of metals and metal ions with DNA
X-ray photoemission studies of the interaction of metals and metal ions with DNA
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DOI：
10.1515/zpch-2021-3037
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发表时间：
2021-11-16
影响因子：
2.5
通讯作者：
Dowben, Peter A.
中科院分区：
文献类型：
--
作者：
Mishra, Esha;Majumder, Subrata;Dowben, Peter A.
X射线光电子能谱（XPS）已被用于研究重金属离子与DNA的相互作用，并取得了一定的成功。XPS的表面灵敏度和选择性有利于识别和表征DNA与金属相互作用的化学和元素结构。本文综述了生物分子与金属相互作用的光电子能谱研究的现状，并对重金属-生物界面相互作用的机理进行了深入研究。具体地，可以看出，金属与DNA的相互作用导致DNA结构的构象变化。
X-ray Photoelectron Spectroscopy (XPS) has been used to study the interactions of heavy metal ions with DNA with some success. Surface sensitivity and selectivity of XPS are advantageous for identifying and characterizing the chemical and elemental structure of the DNA to metal interaction. This review summarizes the status of what amounts to a large part of the photoemission investigations of biomolecule interactions with metals and offers insight into the mechanism for heavy metal-bio interface interactions. Specifically, it is seen that metal interaction with DNA results in conformational changes in the DNA structure.