Salvage CT-guided Transgluteal Cryoablation for Locally Recurrent Prostate Cancer: Initial Experiences
Salvage CT-guided Transgluteal Cryoablation for Locally Recurrent Prostate Cancer: Initial Experiences
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DOI：
10.1016/j.jvir.2013.01.493
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发表时间：
2013-05-01
影响因子：
2.9
通讯作者：
Grenier, Nicolas
中科院分区：
文献类型：
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作者：
Cornelis, Francois;Havez, Marion;Grenier, Nicolas
回顾性评估了计算机断层扫描 (CT) 引导下的经臀方法对无法手术的局部复发性前列腺癌进行挽救性冷冻消融的技术可行性。五名先前接受过放射治疗的患者在全身麻醉下进行了五次手术。中位年龄为 64 岁，治疗前平均前列腺特异性抗原 (PSA) 水平为 2.77 ng/dL（范围：0.56-4.23 ng/dL）。每个冷冻消融手术均在一次疗程中完成。没有并发症的报道。 3个月和6个月的平均PSA水平分别为0.35 ng/dL（范围，0.16-0.54 ng/dL）和0.51 ng/dL（范围，0.09-0.94 ng/dL），平均下降84%（范围，71%-92%）和8.1%（范围，78%-84%）。因此，抢救性 CT 引导下经臀肌冷冻消融术在技术上似乎是可行的。
Technical feasibility of a computed tomography (CT)-guided transgluteal approach for salvage cryoablation of inoperable locally recurrent prostate cancer was evaluated retrospectively. Five procedures were performed under general anesthesia in five patients previously treated with radiation therapy. Median age was 64 years, and average pretreatment prostate-specific antigen (PSA) lever was 2.77 ng/dL (range, 0.56-4.23 ng/dL). Each cryoablation procedure was completed in one session. No complications were reported. Mean 3-month and 6-month PSA levels were 0.35 ng/dL (range, 0.16-0.54 ng/dL) and 0.51 ng/dL (range, 0.09-0.94 ng/dL), respectively, representing Mean decreases of 84% (range, 71%-92%) and 8.1% (range, 78%-84%), respectively. Salvage CT-guided transgluteal cryoablation of the prostate therefore appears technically feasible.