Polyamine involvement in breast cancer phenotype.
Polyamine involvement in breast cancer phenotype.
复制标题
作者：
A. Manni
在这篇综述中，我们将总结目前的证据表明，多胺途径在乳腺癌生物学的两个关键方面，如乳腺癌的发生和肿瘤的进展。我们相信，本文报道的结果为进一步探索抗多胺治疗在辅助治疗和乳腺癌化学预防中的作用提供了强有力的理论基础。
In this review, we will summarize current evidence implicating the polyamine pathway in two critical aspects of breast cancer biology, e.g. mammary carcinogenesis and tumor progression. We believe that the findings reported here provide a strong rationale for further exploring the role of anti-polyamine therapy in the adjuvant setting and in breast cancer chemoprevention.