GenBank.
GenBank.
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DOI：
10.1093/nar/gkv1276
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发表时间：
2016-01-04
影响因子：
14.9
通讯作者：
Sayers EW
中科院分区：
文献类型：
--
作者：
Clark K;Karsch-Mizrachi I;Lipman DJ;Ostell J;Sayers EW
GenBank®（www.ncbi.nlm.nih.gov/genbank/）是一个全面的数据库，包含超过340 000种正式描述的物种的公开可用的核苷酸序列。最近的发展包括提交者的新起始页，转向使用登录.版本标识符而不是GI编号，提交16 S rRNA序列的向导，以及解决数据冗余问题的相同蛋白质报告。GenBank将从各个实验室和大规模测序项目收到的序列数据组织成18个部门，GenBank工作人员在收到数据后分配唯一的登录版本标识符。大多数提交者使用基于网络的BankIt或独立的Sequin程序。与欧洲核苷酸档案馆（ENA）和日本DNA数据库（DDBJ）的每日数据交换确保了全球范围的覆盖。GenBank可通过PubMed检索系统的nuccore、nucest和nucgss数据库访问，该检索系统将这些记录与各种其他数据整合在一起，包括分类学节点、基因组、蛋白质结构和生物医学期刊文献。BLAST提供GenBank和其他序列数据库的序列相似性检索。基因库数据库的完整双月发布和每日更新可通过FTP获得。
GenBank® (www.ncbi.nlm.nih.gov/genbank/) is a comprehensive database that contains publicly available nucleotide sequences for over 340 000 formally described species. Recent developments include a new starting page for submitters, a shift toward using accession.version identifiers rather than GI numbers, a wizard for submitting 16S rRNA sequences, and an Identical Protein Report to address growing issues of data redundancy. GenBank organizes the sequence data received from individual laboratories and large-scale sequencing projects into 18 divisions, and GenBank staff assign unique accession.version identifiers upon data receipt. Most submitters use the web-based BankIt or standalone Sequin programs. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the nuccore, nucest, and nucgss databases of the Entrez retrieval system, which integrates these records with a variety of other data including taxonomy nodes, genomes, protein structures, and biomedical journal literature in PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP.