Histological type and typing of breast carcinomas and the WHO classification changes over time.
Histological type and typing of breast carcinomas and the WHO classification changes over time.
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乳腺癌的组织学类型和分型以及 WHO 分类随时间而变化。
DOI：
10.32074/1591-951x-1-20
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发表时间：
2020-03
期刊：
影响因子：
3.5
通讯作者：
Cserni G
中科院分区：
文献类型：
--
作者：
Cserni G
世界卫生组织刚刚发布了乳腺肿瘤的新分类。本综述旨在探讨乳腺癌的形态学分类，其仍然主要基于组织学特征并遵循组织学分型的传统。它对 WHO 分类及其随时间的变化提供了主观和批判性的观点，并描述了与一些最常见或具有挑战性的乳腺癌相关的变化：更详细地讨论了原位癌、无特殊类型的浸润性乳腺癌、小叶癌、筛状癌、管状癌、粘液性癌、乳头状癌、化生性癌和髓样癌以及顶浆分泌癌。尽管第五版分类并不完美，但它具有所提到的优点以及分类中存在的问题。
The World Health Organization’s new classification of breast tumors has just been published. This review aims to examine the morphological categorization of breast carcinomas which is still principally based on histological features and follows the traditions of histological typing. It gives a subjective and critical view on the WHO classifications and their changes over time, and describes the changes related to some of the most common or challenging breast carcinomas: in situ carcinomas, invasive breast carcinomas of no special type, lobular, cribriform, tubular, mucinous, papillary, metaplastic carcinomas and carcinomas with medullary pattern and those with apocrine differentiation are discussed in more details. Although the 5th edition of the classification is not perfect, it has advantages which are mentioned along with problematic issues of classifications.