The Metabolically Healthy But Obese Phenotype in African Americans
The Metabolically Healthy But Obese Phenotype in African Americans
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DOI：
10.1111/j.1751-7176.2011.00565.x
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发表时间：
2012-02-01
影响因子：
2.8
通讯作者：
Randall, Otelio S.
中科院分区：
文献类型：
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作者：
Cherqaoui, Rabia;Kassim, Thaslim A.;Randall, Otelio S.
肥胖已经成为美国和世界范围内主要的公共卫生问题之一。虽然肥胖与代谢综合征相关，但一些肥胖个体不具有代谢异常的星座，并且被称为代谢健康但肥胖（MHO）的人。关于非裔美国人MHO的患病率和特征的数据有限。作者研究了126名肥胖的非裔美国人，并将MHO表型定义为体重指数≥ 30 kg/m2、高密度脂蛋白胆固醇≥ 40 mg/dL、无2型糖尿病和无动脉高血压的个体。研究了MHO表型与人体测量和代谢指标的相关性，以及年龄对这些相关性的影响。结果表明，36例（28.5%）被鉴定为MHO表型。腰围（WC）和腰臀比（WHR）显著降低（P
Obesity has become one of the leading public health concerns in the United States and worldwide. While obesity is associated with the metabolic syndrome, some obese individuals do not possess the constellation of the metabolic abnormalities and are referred to as metabolically healthy but obese (MHO) persons. Limited data exist on the prevalence and characteristics of the MHO in African Americans. The authors studied 126 obese African Americans and defined the MHO phenotype as an individual with a body mass index >= 30 kg/m(2), high-density lipoprotein cholesterol >= 40 mg/dL, absence of type 2 diabetes mellitus, and absence of arterial hypertension. The correlates of the MHO phenotype with anthropometrical and metabolic indices were examined, as well as the effect of age on these correlates. Results showed that 36 (28.5%) of the individuals were identified with the MHO phenotype. Waist circumference (WC) and waist-to-hip ratio (WHR) were significantly lower (P