Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters
Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters
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DOI：
10.1093/bioinformatics/18.1.198
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发表时间：
2002-01-01
期刊：
影响因子：
5.8
通讯作者：
Brusic, V
中科院分区：
文献类型：
--
作者：
Bajic, VB;Seah, SH;Brusic, V
摘要：Dragon Promoter Finder(DPF)通过预测转录起始点(TSS)的位置来定位脊椎动物DNA序列中的RNA聚合酶11启动子。DPF的算法使用了三个功能区(启动子、外显子和内含子)的传感器和一个人工神经网络(ANN)。在一个庞大和多样化的评估集上的结果表明，与其他三个启动子查找程序相比，DPF具有更好的预测能力。可用性：http://sdmc.krdl.org.sg:8080/promoter/Contact：bajicv@krdl.org.sg。
Sum: Dragon Promoter Finder (DPF) locates RNA polymerase 11 promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN).Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.Availability: http://sdmc.krdl.org.sg:8080/promoter/Contact: bajicv@krdl.org.sg.