P1 and P1' para-fluoro phenyl groups show enhanced binding and favorable predicted pharmacological properties: structure-based virtual screening of extended lopinavir analogs against multi-drug resistant HIV-1 protease.
P1 and P1' para-fluoro phenyl groups show enhanced binding and favorable predicted pharmacological properties: structure-based virtual screening of extended lopinavir analogs against multi-drug resistant HIV-1 protease.
复制标题
P1 和 P1 对氟苯基显示出增强的结合力和有利的预测药理学特性：针对多重耐药 HIV-1 蛋白酶的扩展洛匹那韦类似物的基于结构的虚拟筛选。
DOI：
10.1016/j.jmgm.2013.10.010
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发表时间：
2014
影响因子：
2.9
通讯作者：
Kovari,LadislauC
中科院分区：
文献类型：
--
作者：
Yedidi,RavikiranS;Liu,Zhigang;Kovari,IuliaA;Woster,PatrickM;Kovari,LadislauC
