Reconstructing Historical Exposures to Respirable Dust and Respirable Silica in the Taconite Mining Industry for 1955-2010.

Reconstructing Historical Exposures to Respirable Dust and Respirable Silica in the Taconite Mining Industry for 1955-2010.
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重建 1955-2010 年铁燧岩采矿业中可吸入粉尘和可吸入二氧化硅的历史暴露情况。

DOI:
10.1093/annweh/wxab099
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发表时间:
2022
影响因子:
2.6
通讯作者:
Ramachandran,Gurumurthy
Ramachandran,Gurumurthy
中科院分区:
医学4区
文献类型:
--
作者:
Shao,Yuan;Hwang,Jooyeon;MacLehose,RichardF;Alexander,BruceH;Mandel,JeffreyH;Raynor,PeterC;Ramachandran,Gurumurthy

文献摘要

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本研究的目的是重建1955年至2010年明尼苏达州塔可石工业工人的可吸入二氧化硅(RS)和可吸入粉尘(RD)暴露历史,作为评估塔可石粉尘成分暴露与呼吸道疾病发展之间关系的几项流行病学研究的一部分。利用9127 RS和19391 RD的职业卫生历史测量数据编制了职业暴露矩阵。从多个来源提取历史RS和RD数据,并将其分为七个矿山,然后分为八个部门[集中,破碎,看门,采矿,办公室/控制室,制粒,车间(移动)和车间(固定)]。在每个部门中,我们应用了一个两水平随机截距回归模型,该模型假设Y的自然对数(RD或RS浓度)随时间以恒定速率变化。在所有预测RD和RS值中,我们发现较大的RD值位于以下部门:破碎,浓缩,造粒和车间(移动)。较大的RS值仅位于破碎或车间(移动)。历史RD和RS暴露的年变化率在- 3.3和3.2%之间。不同矿种/部门粉尘中二氧化硅含量不同,F矿(破碎)最高,为29.3%,B矿(造球)最低,为2.1%。预测的历史RD和RS算术平均暴露量分别在<0.075 ~ 3.14 mg m - 3和<0.005 ~ 0.36 mg m - 3之间。这项研究的结果是按我、部门和年份为RD和RS进行流行病学研究的JEM。
The goal of this study was to reconstruct the historical respirable silica (RS) and respirable dust (RD) exposures of workers in the Minnesota taconite industry from 1955 to 2010 as part of several epidemiological studies for assessing the association between exposure to components of taconite dusts and the development of respiratory diseases. A job-exposure matrix (JEM) was developed that uses 9127 RS and 19 391 RD occupational hygiene historical measurements. Historical RS and RD data were extracted from several sources and were grouped into seven mines and then into eight departments [Concentrating, Crushing, Janitor, Mining, Office/control room, Pelletizing, Shop (mobile), and Shop (stationary)]. Within each department, we applied a two-level random-intercept regression model which assumes that the natural log of Y (RD or RS concentration) changes over time at a constant rate. Among all predicted RD and RS values, we found that larger RD values were located in the following departments: Crushing, Concentrating, Pelletizing, and Shop (mobile). Larger RS values were located only in either Crushing or Shop (mobile). The annual rates of change for historical RD and RS exposures were between −3.3 and 3.2%. The silica percentage in the dust varied by mine/department with the highest value of 29.3% in Mine F (Crushing) and the lowest value of 2.1% in Mine B (Pelletizing). The predicted historical RD and RS arithmetic mean exposures ranged between <0.075 and 3.14 mg m−3, and between <0.005 and 0.36 mg m−3, respectively. The result of this study is a JEM by mine, department, and year for RD and RS for epidemiological studies.