Synthesis, characterisation, and biological studies of CdTe quantum dot-naproxen conjugates

Synthesis, characterisation, and biological studies of CdTe quantum dot-naproxen conjugates
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DOI:
10.1002/cmdc.200600232
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发表时间:
2007-02-01
期刊:
影响因子:
3.4
通讯作者:
Evans, Paul
Evans, Paul
中科院分区:
医学4区
文献类型:
--
作者:
Byrne, Stephen J.;le Bon, Bertrand;Evans, Paul

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第一个萘普生-QD 缀合物已被合成并研究。这些缀合物表现出有趣的光物理特性、在侵蚀性酶介质中良好的稳定性以及在巨噬细胞 (THP-1) 细胞中的细胞定位。这些纳米复合材料可能具有作为药物输送和细胞成像剂的潜力。
The first naproxen-QD conjugates have been synthesised and investigated. These conjugates demonstrated interesting photophysical properties, good stability in an aggressive enzymatic medium, and cellular localisation in macrophage (THP-1) cells. These nano-composites might have the potential to act as drug delivery and cellular imaging agents.