The Angiomotins--from discovery to function.
The Angiomotins--from discovery to function.
复制标题
血管植物 - 从功能中发现。
DOI:
10.1016/j.febslet.2014.02.006
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发表时间:
2014-08-19
期刊:
影响因子:
3.5
通讯作者:
Kissil JL
中科院分区:
文献类型:
--
作者:
Moleirinho S;Guerrant W;Kissil JL
Angiomotins were originally identified as angiostatin binding proteins and implicated in the regulation of endothelial cell migration. Recent studies have shed light on the role of Angiomotins and other members of the Motin protein family in epithelial cells and in pathways directly linked to the pathogenesis of cancer. In particular, Motins have been shown to play a role in signaling pathways regulated by small G-proteins and the Hippo-YAP pathway. In this review the role of the Motin protein family in these signaling pathways will be described and open questions will be discussed.
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影响因子:
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