Resilience in the Face of Pandemic: The Impact of COVID-19 on the Psychologic Morbidity and Health-Related Quality of Life Among Women With Ovarian Cancer
Resilience in the Face of Pandemic: The Impact of COVID-19 on the Psychologic Morbidity and Health-Related Quality of Life Among Women With Ovarian Cancer
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DOI：
10.1200/op.21.00514
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发表时间：
2022-06-01
影响因子：
4
通讯作者：
Lee, Nita K.
中科院分区：
文献类型：
--
作者：
Javellana, Melissa;Hlubocky, Fay J.;Lee, Nita K.
目的：2019冠状病毒病大流行给卵巢癌幸存者带来了新的挑战。本研究旨在评估大流行引起的心理发病率和医疗保健的改变。方法：我们联系了我们机构的晚期卵巢癌幸存者，让他们参与一项基于电话的横断面定量调查研究，评估与大流行相关的心理发病率。使用有效的测量方法探索心理领域：健康相关生活质量（HRQOL；癌症治疗功能评估[FACT-G7]），焦虑（广泛性焦虑症-7 [GAD7]），抑郁（患者健康问卷-2 [PHQ2]），全球健康患者报告的结果测量信息系统-全球身体健康/全球心理健康（promisi - gmh /GPH），恢复力（简短恢复力量表）和孤独感（英语纵向老龄化研究）。新的COVID-19大流行问题来自我们部门开展的一项更大的调查。结果：接触的患者中有59%（104例中的61例）完成了调查。四分之一的受访者具有高弹性，只有10%的受访者具有低弹性。只有一名患者的抑郁症筛查呈阳性，两名患者的焦虑症筛查呈阳性。43%的受访者表示孤独感增加了。患者总体HRQOL良好（中位数= 21；范围= 6-28）。很少有患者经历治疗延迟，只有4人经历化疗中断，2人报告手术延迟。多元回归分析显示，高FACT-G7 HRQOL与年龄介于65岁之间、自我报告的心理健康状况高、高恢复力和停止化疗有关。癌症复发和高恢复力可以预测较低的COVID-19担忧。结论：尽管2019冠状病毒病大流行影响深远，但卵巢癌幸存者的HRQOL得到了维持。年龄越大、适应能力越强、心理健康状况越好以及停止化疗预示着较好的HRQOL。面对大流行，卵巢癌幸存者仍能保持复原力，临床医生的支持对保护这一宝贵的个人资源至关重要。在2019冠状病毒病大流行期间，卵巢癌幸存者的复原力支持了他们的福祉
PURPOSE: The COVID-19 pandemic has created new challenges for ovarian cancer survivors. This study aims to evaluate the psychologic morbidity and alterations in medical care caused by the pandemic. METHODS: Advanced-stage ovarian cancer survivors at our institution were contacted for participation in a cross-sectional telephone-based quantitative survey study assessing pandemic-related psychologic morbidity. Psychologic domains using validated measures were explored: health-related quality of life (HRQOL; functional assessment of cancer therapy [FACT-G7]), anxiety (generalized anxiety disorder-7 [GAD7]), depression (Patient Health Questionnarie-2 [PHQ2]), global health Patient-Reported Outcomes Measurement Information System - Global Physical Health/Global Mental Health (PROMIS-GMH/GPH), resilience (brief resilience scale), and loneliness (English Longitudinal Study on Aging). Novel COVID-19 pandemic questions were drawn from a larger survey developed in our department. RESULTS: Fifty-nine percent (61 of 104) of contacted patients completed the survey. One quarter of respondents had high resilience, with only 10% reporting low resilience. Only one patient screened positive for depression, and two for anxiety. Increased loneliness was reported by 43% of respondents. Patients' overall HRQOL was good (median = 21; range = 6-28). Few patients experienced treatment delays, with only four experiencing chemotherapy interruption and two reporting surgical delays. Multiple regression analyses revealed that high FACT-G7 HRQOL was predicted by age > 65 years, high self-reported mental health, high resilience, and being off chemotherapy. Lower COVID-19 concern was predicted by recurrent cancer and high resilience. CONCLUSION: Despite the far-reaching impact of the COVID-19 pandemic, ovarian cancer survivors' HRQOL has been maintained. Older age, high resilience, high mental health, and being off chemotherapy predicted better HRQOL. Ovarian cancer survivors remain resilient in the face of the pandemic, and the support of clinicians to preserve this invaluable personal resource is critical for well-being.Ovarian cancer survivors' resilience has supported their well-being during the COVID-19 pandemic