Is preterm delivery genetically determined?
Is preterm delivery genetically determined?
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早产是由基因决定的吗？
DOI：
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发表时间：
1991
影响因子：
2.8
通讯作者：
Peter W. Lunt
中科院分区：
文献类型：
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作者：
H. Wildschut;L. Lumey;Peter W. Lunt
令人惊讶的是，早产的遗传学在文献中很少受到关注。可能的解释是无法获得准确的信息妊娠期的长度在家庭研究和异质性的这种疾病。与许多研究认为遗传和环境方差对出生体重总方差的相对贡献相反，很少有研究探讨了人类妊娠期的遗传基础，有人认为，需要遗传和流行病学的方法来分离遗传和环境对妊娠期的影响。
Surprisingly, the genetics of preterm delivery have received very little attention in the literature. Possible explanations are the inability to obtain accurate information on the length of gestation in family studies and the heterogeneous nature of this disorder. In contrast to the many studies which consider the relative contribution of both genetic and environmental variance to the total variance of birthweight, few studies have examined the genetic basis of the duration of gestation in man. It is argued that both genetic and epidemiological approaches are needed to separate the effects of heredity and the environment on the duration of gestation.