Relation between red nucleus discharge and movement parameters in trained macaque monkeys.
Relation between red nucleus discharge and movement parameters in trained macaque monkeys.
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受训猕猴红核放电与运动参数之间的关系。
DOI：
10.1113/jphysiol.1985.sp015566
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
Kohlerman,NJ
中科院分区：
文献类型：
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作者：
Gibson,AR;Houk,JC;Kohlerman,NJ
对前一篇论文中描述的33个大细胞红核细胞进行了相关和回归分析。我们试图测试个体跟踪运动的参数与相应的神经放电爆发之间的可靠关系。以下爆发和运动参数之间存在高度相关性：(i)爆发潜伏期与运动潜伏期；（ii）爆发持续时间与移动持续时间；（iii）爆发频率与运动速度的关系；（iv）爆发中尖峰的数量与运动幅度的关系。根据持续时间、速度和振幅相关系数的平均值对细胞进行排序。前20个细胞的平均相关系数为0.69 ~ 0.88。这些病例被认为最有可能揭示红核的控制功能，以下几点参考这个样本。猝发导致运动偏移118 +/‐23 ms，猝发偏移导致运动偏移50 +/‐38 ms。爆发持续时间随着移动持续时间的增加而增加（r = 0.87 +/‐0.11）。爆发的持续时间大致等于运动持续时间（斜率为0.99 +/‐0.16）加上一个常数（72 +/‐34 ms），范围很广。爆炸期间的平均放电率随平均移动速度的增加而增加（r = 0.69 +/‐0.15）。该关系的斜率为0.36 +/‐0.21（脉冲/秒）/（度/秒）。回归线具有一致的向上偏移量（56 +/‐15脉冲/s），超过了自发放电率（17 +/‐10脉冲/s）。脉冲中尖峰的数量随运动幅度的增加而增加，与速度无关（r = 0.72 +/‐0.11）。关系的斜率为0.62尖峰/度，偏移量为13 +/‐4尖峰。首选的运动是手部协调15例，手指协调3例，手肘协调1例，肩关节协调1例。当这些细胞以交替运动进行测试时，故障率（爆发不伴随运动的情况）从1.4%增加到20%，相关系数通常很低且缺乏显著性。前20名的细胞具有方向性特异性响应，前置时间方差小，调制深度大（41 - 118脉冲/秒），故障率低。不能显示强参数相关性的单元格通常具有一个或多个前一种属性。与个体运动的高参数相关性似乎是关系的特别限制性标准。（摘要删节为400字）
Correlation and regression analyses were performed on thirty‐three of the magnocellular red nucleus cells described in the previous paper. We sought to test for reliable relations between the parameters of individual tracking movements and corresponding bursts of neural discharge. High correlations were found between the following burst and movement parameters: (i) burst latency versus movement latency; (ii) burst duration versus movement duration; (iii) burst frequency versus movement velocity and (iv) number of spikes in the burst versus movement amplitude. Cells were ranked according to the average of the duration, velocity and amplitude correlation coefficients. The top twenty cells had average correlation coefficients ranging from 0.69 to 0.88 for their preferred movement. These cases were judged most likely to reveal the control functions of the red nucleus, and the following points refer to this sample. Burst onset led movement onset by 118 +/‐ 23 ms, and burst offset led movement offset by 50 +/‐ 38 ms. Burst duration increased as the duration of the movement increased (r = 0.87 +/‐ 0.11). The duration of the burst was approximately equal to movement duration (slope of 0.99 +/‐ 0.16) plus a constant (72 +/‐ 34 ms) throughout a broad range. Average discharge rate during the burst increased with average movement velocity (r = 0.69 +/‐ 0.15). The slope of the relation was 0.36 +/‐ 0.21 (pulses/s)/(deg/s) of joint rotation. The regression lines had consistent upward offsets (56 +/‐ 15 pulses/s) that exceeded the spontaneous discharge rate (17 +/‐ 10 pulses/s). The number of spikes in the burst increased with movement amplitude independent of velocity (r = 0.72 +/‐ 0.11). The slope of the relation was 0.62 spikes/deg and the offset was 13 +/‐ 4 spikes. The preferred movement was co‐ordinated hand in fifteen cases, digit in three, elbow in one and shoulder in one. When these cells were tested with an alternate movement, the failure rate (cases in which a burst did not accompany a movement) increased from 1.4 to 20%, and the correlation coefficients generally were low and lacked significance. Cells in the top twenty had directionally specific responses, low variance in lead time, large depths of modulation (41‐118 pulses/s) and low failure rates. Cells that failed to show strong parametric correlations often had one or more of the former attributes. It appears that high parametric correlations with individual movements are particularly restrictive criteria of relatedness.(ABSTRACT TRUNCATED AT 400 WORDS)