Infrared and skin: Friend or foe.
Infrared and skin: Friend or foe.
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红外线和皮肤：朋友或敌人。
DOI：
10.1016/j.jphotobiol.2015.12.014
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发表时间：
2016-02
期刊：
影响因子：
--
通讯作者：
Hamblin MR
中科院分区：
文献类型：
--
作者：
Barolet D;Christiaens F;Hamblin MR
在过去的十年中，已经提出太阳的IR-A波长可能对人类皮肤有害，并且防晒剂除了其保护免受UV-B和UV-A的期望效果之外，还应该保护免受IR-A（甚至可能是可见光）。几项研究表明，近红外线可能会损害皮肤胶原蛋白的含量，通过增加MMP-1的活性，在相同的方式是已知的紫外线。不幸的是，这些研究中使用的人造近红外光源并不能代表太阳辐照度。然而，很少有人提到硬币的另一面。本文将重点介绍关键信息，表明当皮肤暴露于适当的辐照度/剂量的IR-A辐射时，IR-A可能比有害的更有益，类似于人们在真实的生活中接受的日常阳光照射。从进化的角度来看，IR-A甚至可能对皮肤进行预处理--这一过程称为紫外线预防--因为暴露在清晨阳光下的IR-A波长下可能会使皮肤为即将到来的中午有害紫外线做好准备。因此，IR-A似乎是解决方案，而不是问题。它对皮肤的好处多于坏处。这本质上是一个强度的问题，以及我们如何从太阳中学习。
In the last decade, it has been proposed that the sun's IR-A wavelengths might be deleterious to human skin and that sunscreens, in addition to their desired effect to protect against UV-B and UV-A, should also protect against IR-A (and perhaps even visible light). Several studies showed that NIR may damage skin collagen content via an increase in MMP-1 activity in the same manner as is known for UVR. Unfortunately, the artificial NIR light sources used in such studies were not representative of the solar irradiance. Yet, little has been said about the other side of the coin. This article will focus on key information suggesting that IR-A may be more beneficial than deleterious when the skin is exposed to the appropriate irradiance/dose of IR-A radiation similar to daily sun exposure received by people in real life. IR-A might even precondition the skin – a process called photoprevention - from an evolutionary standpoint since exposure to early morning IR-A wavelengths in sunlight may ready the skin for the coming mid-day deleterious UVR. Consequently IR-A appears to be the solution, not the problem. It does more good than bad for the skin. It is essentially a question of intensity and how we can learn from the sun.