Distribution of three arbovirus antibodies among monkeys (Macaca fascicularis) in the Philippines
Distribution of three arbovirus antibodies among monkeys (Macaca fascicularis) in the Philippines
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DOI：
10.1034/j.1600-0684.2003.00015.x
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发表时间：
2003-04-01
影响因子：
0.7
通讯作者：
Natividad, FF
中科院分区：
文献类型：
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作者：
Inoue, S;Morita, K;Natividad, FF
1999年，在菲律宾吕宋岛的一个猴场采集了54只健康猴的血清，用IgM捕捉法和间接抗体夹心法检测了登革热(DEN)、乙型脑炎(JE)和基孔肯雅(CHIK)病毒的存在。IgM-EL ISA对DEN、JE和CHIK的阳性率分别为3.7%、35.2%和14.8%。间接免疫吸附试验的阳性率较高，对黄病毒(乙脑或登革热)的阳性率为100%，对Chik病毒的阳性率为59.3%。结果表明，在菲律宾的猴子中，黄病毒感染的流行率很高，如乙脑和登革热，而Chik病毒感染的流行率较低。这些发现表明，这些病毒可能存在不同的传播周期。
Serum samples from 54 monkeys were collected from healthy individuals in a monkey farm in Luzon island, Philippines, in 1999, and examined by IgM-capture ELISA and indirect IgG ELISA for the presence of dengue (DEN), Japanese encephalitis (JE) and chikungunya (CHIK) viruses. The positive rates for IgM ELISA were 3.7, 35.2 and 14.8% against DEN, JE and CHIK, respectively. Higher positive rates were obtained when indirect IgG ELISA was used: 100% against flaviviruses (JE or DEN) and 59.3% against CHIK virus. The results indicate a high prevalence of flavivirus infections such as JE and DEN, and a lesser prevalence of CHIK virus infections, among monkeys in the Philippines. These findings suggest possible sylvatic transmission cycles of these viruses.