Extracorporeal photochemotherapy as adjunctive treatment in juvenile dermatomyositis: a case report.
Extracorporeal photochemotherapy as adjunctive treatment in juvenile dermatomyositis: a case report.
复制标题
体外光化疗作为青少年皮肌炎的辅助治疗：病例报告。
作者：
Annemarie De Wilde;F. DiSpaltro;Alex Geller;Ilona S. Szer;A. Klainer;Emil Bisaccia
致编辑。 —青少年皮肌炎 (JDMS) 是一种炎症性肌病，其特征为典型的天芥菜皮疹、近端肌无力和肌酶水平升高。体液和细胞的自身免疫与发病机制有关。高剂量类固醇和 ag 光采术开始后数月 在甲氨蝶呤和光采术联合治疗过程中对患者进行酶研究。 ALT表示丙氨酸转氨酶； AST、天冬氨酸转氨酶[不适]和 ULN，正常上限。积极的物理治疗是主要的治疗方法。对于对类固醇[疾病]无反应或不耐受的患者，可使用甲氨蝶呤、细胞毒性药物、全身照射和血浆置换等治疗方式。1体外光化学疗法已被报道用于治疗自身免疫性疾病。2,3我们描述了一名 JDMS 患者，其疾病在单独使用甲氨蝶呤治疗后出现进展，并且似乎对体外光采术的辅助治疗有反应。病例报告——我们的患者是一位 18 岁的女性，
To the Editor. —Juvenile dermatomyositis (JDMS) is an inflammatory myopathy characterized by a classic heliotrope rash, proximal muscle weakness, and elevated muscle enzyme levels. Autoimmunity, both humoral and cellular, is implicated in the pathogenesis. High doses of steroids and ag Months After Start of Photopheresis Patient's enzyme studies throughout the course of combined therapy with methotrexate and photopheresis. ALT indicates alanine aminotransferase; AST, aspartate aminotransferase[ill] and ULN, upper limit of normal. gressive physical therapy are the mainstay of treatment. In patients unresponsive to or intolerant of steroid [ill] therapeutic modalities such as methotrexate, cytotoxic drugs, total body irradiation, and plasmapheresis are used.1Extracorporeal photochemotherapy has been reported for the treatment of autoimmune diseases.2,3We describe a patient with JDMS whose disease progressed on treatment with methotrexate alone and who appears to respond to adjunctive therapy with extracorporeal photopheresis. Report of a Case .—Our patient, an 18-year-old woman, developed
体外光化疗治疗自身免疫性疾病：进行性系统性硬化症。
DOI：
--
发表时间：
1989
期刊：
The Yale journal of biology and medicine
影响因子：
--
作者：
Rook,AH;Freundlich,B;Nahass,GT;Washko,R;Macelis,B;Skolnicki,M;Bromley,P;Witmer,WK;Jegasothy,BV
通讯作者：
Jegasothy,BV
体外光化疗治疗类风湿性关节炎。
影响因子：
--
作者：
Malawista,SE;Trock,DH;Edelson,RL
通讯作者：
Edelson,RL