Cellulose nanocrystals based clove oil Pickering emulsion for enhanced antibacterial activity.
Cellulose nanocrystals based clove oil Pickering emulsion for enhanced antibacterial activity.
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DOI：
10.1016/j.ijbiomac.2020.12.027
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发表时间：
2020-12
影响因子：
8.2
通讯作者：
Huaping Yu;Guiting Huang;Yueqin Ma;Yang Liu;Xiaoying Huang;Qin Zheng;Pengfei Yue;Ming Yang
中科院分区：
文献类型：
--
作者：
Huaping Yu;Guiting Huang;Yueqin Ma;Yang Liu;Xiaoying Huang;Qin Zheng;Pengfei Yue;Ming Yang
采用挥发油Pickering乳液（CO-PE）制备了一种有效的抗菌体系。以羧甲基纤维素钠改性的纤维素纳米晶（CNC）作为CO-PE的稳定剂，采用环境友好的均质化技术制备了纳米纤维素纳米晶。研究了CNC浓度、均质压力、CO浓度、离子浓度和pH值等因素对CO-PE形成和稳定性的影响，并对CO-PE对大肠杆菌的抗菌性能进行了研究。coliandS.以最小抑菌浓度（MIC）为指标，对金黄色葡萄球菌进行体外抑菌试验。结果表明：1%CNC稳定的CO-PE液滴粒径小，表面粗糙，在高pH值或盐浓度下具有良好的稳定性，这是由于CNC存在于液滴界面。在相同的CO浓度下，CNC稳定的CO-PE表现出更高的抗菌活性，这可能是由于有效地粘附在细菌膜上。因此，本研究将为载精油的Pickering乳液在食品等行业的抗菌应用提供新的思路。
An effective antibacterial system was developed by using clove essential oil Pickering emulsion (CO-PE). The carboxymethyl cellulose sodium modified cellulose nanocrystals (CNC) was used as the stabilizer of CO-PE, which were prepared by environmentally friendly approach of homogenization technology. The factors affecting the formation and stability of CO-PE were studied, such as CNC concentration, homogenization pressure, CO concentration and ionic concentration and pH. And the antibacterial performance of CO-PE againstE. coliandS. aureuswas investigated by determining the minimal inhibitory concentration (MIC). The results showed that 1% CNC stabilized CO-PE exhibited small droplet size and rough surface, and had good stability at high pH values or salt concentration, owing to the presence of CNC on interface of droplet. And the CNC-stabilized CO-PE exhibited higher antimicrobial activity at equivalent CO concentration, which might be attributed to efficiently adhere to bacterial membrane. Therefore, our research would provide new insights for antibacterial application of Pickering emulsions loading essential oils in the food and other industries.