Multidisciplinary Meeting on Male Breast Cancer: Summary and Research Recommendations
Multidisciplinary Meeting on Male Breast Cancer: Summary and Research Recommendations
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DOI：
10.1200/jco.2009.25.5729
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发表时间：
2010-04-20
影响因子：
45.3
通讯作者：
Cardoso, Fatima
中科院分区：
文献类型：
--
作者：
Korde, Larissa A.;Zujewski, Jo Anne;Cardoso, Fatima
男性乳腺癌是一种罕见的疾病，占全球所有乳腺癌诊断的不到1%。大多数关于男性乳腺癌的数据来自小型的单机构研究，由于数据的缺乏，男性乳腺癌的最佳治疗方法尚不清楚。本文总结了由美国国立卫生研究院罕见疾病办公室和美国国立癌症研究所癌症流行病学和遗传学以及癌症治疗和诊断部门主办的男性乳腺癌多学科国际会议。会议包括来自流行病学、遗传学、病理学和分子生物学、保健服务研究、临床肿瘤学和宣传界的代表，对数据进行了全面审查。发言着重强调了男性和女性乳腺癌之间的差异和相似之处。为了提高我们对男性乳腺癌的认识，国际财团是必要的。因此，国际乳腺组织和北美乳腺癌组织共同努力，制定了一项国际男性乳腺癌计划，并汇集了流行病学数据、临床信息和肿瘤标本。这项国际合作也将促进未来临床试验的规划，以解决男性乳腺癌治疗中的基本问题。J Clin Oncol 28：2114- 2122. (C)2010年美国临床肿瘤学会
Male breast cancer is a rare disease, accounting for less than 1% of all breast cancer diagnoses worldwide. Most data on male breast cancer comes from small single-institution studies, and because of the paucity of data, the optimal treatment for male breast cancer is not known. This article summarizes a multidisciplinary international meeting on male breast cancer, sponsored by the National Institutes of Health Office of Rare Diseases and the National Cancer Institute Divisions of Cancer Epidemiology and Genetics and Cancer Treatment and Diagnosis. The meeting included representatives from the fields of epidemiology, genetics, pathology and molecular biology, health services research, and clinical oncology and the advocacy community, with a comprehensive review of the data. Presentations focused on highlighting differences and similarities between breast cancer in males and females. To enhance our understanding of male breast cancer, international consortia are necessary. Therefore, the Breast International Group and North American Breast Cancer Group have joined efforts to develop an International Male Breast Cancer Program and to pool epidemiologic data, clinical information, and tumor specimens. This international collaboration will also facilitate the future planning of clinical trials that can address essential questions in the treatment of male breast cancer. J Clin Oncol 28: 2114- 2122. (C) 2010 by American Society of Clinical Oncology