Association Between Pre-Ablation Glycemic Control and Outcomes Among Patients With Diabetes Undergoing Atrial Fibrillation Ablation
Association Between Pre-Ablation Glycemic Control and Outcomes Among Patients With Diabetes Undergoing Atrial Fibrillation Ablation
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DOI：
10.1016/j.jacep.2019.05.018
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发表时间：
2019-08-01
影响因子：
7
通讯作者：
Wazni, Oussama
中科院分区：
文献类型：
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作者：
Donnellan, Eoin;Aagaard, Philip;Wazni, Oussama
本研究的目的是调查消融术后改善血糖控制对房颤（AF）复发率的影响。背景糖尿病与AF发生率增加有关。改善消融前血糖控制的影响尚不清楚。方法对298例接受AF消融术的糖尿病患者进行了12个月的消融前血糖控制趋势研究。在消融后平均25.92 +/- 20.26个月的随访期间获得复发数据。结果消融时较高的糖化血红蛋白（HbA（1c））与较高的消融后复发率相关。消融时HbA（1c）>9%的患者中，超过三分之二（68.75%）的患者复发AF，而HbA（1c）>9%的患者复发AF的比例为32.4%。
OBJECTIVES The aim of this study was to investigate the impact of improved glycemic control on atrial fibrillation (AF) recurrence rates after ablation.BACKGROUND Diabetes is associated with increased rates of AF. The impact of improved pre-ablation glycemic control remains unknown.METHODS The 12-month pre-ablation trends in glycemic control were studied in 298 patients with diabetes undergoing AF ablation. Recurrence data were obtained during a mean follow-up period of 25.92 +/- 20.26 months post-ablation.RESULTS Higher glycated hemoglobin (HbA(1c)) at the time of ablation was associated with higher post-ablation recurrence rates. More than two-thirds (68.75%) of patients with HbA(1c) >9% at the time of ablation developed recurrent AF, compared with 32.4% of those with HbA(1c)