Molecular genetic analysis of remains of a 2,000-year-old human population in China - and its relevance for the origin of the modern Japanese population
Molecular genetic analysis of remains of a 2,000-year-old human population in China - and its relevance for the origin of the modern Japanese population
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DOI：
10.1086/302197
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发表时间：
1999-01-01
影响因子：
9.8
通讯作者：
Ueda, S
中科院分区：
文献类型：
--
作者：
Oota, H;Saitou, N;Ueda, S
我们从中国山东半岛义溪遗址（距今约2,000年）出土的人类遗骸中提取DNA，通过PCR扩增，测定了其线粒体D环区的核苷酸序列。古代彝溪人的核苷酸多样性与现代人群相似。根据1，298个个体的414种mtDNA类型构建的系统发育网络，将亚洲和环太平洋地区的现代人类分为6个辐射组。本文用辐射群频率分布和群体间遗传距离两个指标对古代义溪人与现代亚洲和环太平洋地区的人群进行了比较，结果表明古代义溪人与现代台湾汉族人群的遗传关系最近。与蒙古人、日本本土人和朝鲜人相比，益西人与阿伊努人和琉球人的遗传亲缘关系更近，与绳文人和弥生人的遗传相似性更小。
We extracted DNA from the human remains excavated from the Yixi site (similar to 2,000 years before the present) in the Shandong peninsula of China and, through PCR amplification, determined nucleotide sequences of their mitochondrial D-loop regions. Nucleotide diversity of the ancient Yixi people was similar to those of modern populations. Modern humans in Asia and the circum-Pacific region are divided into six radiation groups, on the basis of the phylogenetic network constructed by means of 414 mtDNA types from 1,298 individuals. We compared the ancient Yixi people with the modern Asian and the circum-Pacific populations, using two indices: frequency distribution of the radiation groups and genetic distances among populations, Both revealed that the closest genetic relatedness is between the ancient Yixi people and the modern Taiwan Han Chinese. The Yixi people show closer genetic affinity with Mongolians, mainland Japanese, and Koreans than with Ainu and Ryukyu Japanese and less genetic resemblance with Jomon people and Yayoi people, their predecessors and contemporaries, respectively, in ancient Japan.