Biological, clinical, and ethical advances of placebo effects.
Biological, clinical, and ethical advances of placebo effects.
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DOI：
10.1016/s0140-6736(09)61706-2
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发表时间：
2010-02-20
期刊：
影响因子：
168.9
通讯作者：
Benedetti, Fabrizio
中科院分区：
文献类型：
--
作者：
Finniss, Damien G.;Kaptchuk, Ted J.;Miller, Franklin;Benedetti, Fabrizio
多年来，安慰剂一直被概念化，因为它们的惰性含量和它们在临床试验和临床实践中作为对照的用途。最近的研究表明，安慰剂效应是真正的心理生物学现象，可归因于整体治疗背景，安慰剂效应在实验室和临床环境中都是强大的。也有证据表明，安慰剂效应可以存在于临床实践中，即使没有给予安慰剂。实验室和临床研究的进一步促进和整合将使常规临床护理中固有的安慰剂机制的伦理利用以及主要促进安慰剂效应的治疗的潜在用途取得进展。
For many years, placebos have been conceptualised by their inert content and their use as controls in clinical trials and treatments in clinical practice. Recent research demonstrates that placebo effects are genuine psychobiological phenomenon attributable to the overall therapeutic context, and that placebo effects can be robust in both laboratory and clinical settings. Evidence has also emerged that placebo effects can exist in clinical practice, even if no placebo is given. Further promotion and integration of laboratory and clinical research will allow advances in the ethical harnessing of placebo mechanisms that are inherent in routine clinical care and the potential use of treatments to primarily promote placebo effects.