Views on Personalized Medicine: Do the Attitudes of African American and White Prescription Drug Consumers Differ?
Views on Personalized Medicine: Do the Attitudes of African American and White Prescription Drug Consumers Differ?
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DOI：
10.1159/000242199
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发表时间：
2010-01-01
影响因子：
1.7
通讯作者：
De Marco, M.
中科院分区：
文献类型：
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作者：
De Marco, M.
目的：尽管药物基因组学的最新进展使得利用基因测试来确定对患者最好的药物成为可能，但人们对患者如何看待这种程序知之甚少。作为社区-学术合作伙伴关系的一部分，这项研究的目的是：(1)处方药消费者对个性化药物和药物配伍基因测试的态度和看法是什么，非裔美国人和白人患者之间有什么不同？(2)患者对基于种族的处方的态度和看法是什么，非裔美国人和白人患者之间有什么不同？方法：我们进行了6个焦点小组，2个是白人参与者，4个是非裔美国人参与者。对焦点小组进行录音、转录和分析，以确定共同的主题。结果：我们的研究结果表明，个人化医学和基因检测虽然没有被外行人很好地理解，但被认为是医学上的积极进展。然而，参与者也表达了对这些进步的担忧，这些进步因种族而异。结论：这项研究指出，随着我们走向这项技术的更广泛使用，需要包括高危社区的观点。版权所有(C)2009 S.Karger AG，巴塞尔
Aims: Although recent advances in pharmacogenomics are making possible the use of genetic testing to determine the best medication for patients, little is known about how patients view such procedures. The aims for this study that were developed collaboratively as part of a community-academic partnership are: (1) What are the attitudes and perceptions of prescription drug consumers concerning personalized medicine and genetic testing for drug compatibility and how do they differ between African American and white patients? (2) What are the attitudes and perceptions of patients concerning race-based prescribing and how do they differ between African American and white patients? Methods: We conducted 6 focus groups, 2 with white participants and 4 with African American participants. Focus groups were audio-recorded, transcribed, and analyzed to ascertain common themes. Results: Our results suggest that personalized medicine and genetic testing, though not well understood by lay persons, were considered positive advances in medicine. However, participants also voiced concerns about these advances that differed by race. Conclusion: This study points to the need to include perspectives of at-risk communities as we move toward wider use of this technology. Copyright (C) 2009 S. Karger AG, Basel