Outcomes of indwelling metallic stents for malignant extrinsic ureteral obstruction
Outcomes of indwelling metallic stents for malignant extrinsic ureteral obstruction
复制标题
DOI：
10.1111/iju.13500
复制
发表时间：
2018-03-01
影响因子：
2.6
通讯作者：
Nakatani, Tatsuya
中科院分区：
文献类型：
--
作者：
Asakawa, Jumpei;Iguchi, Taro;Nakatani, Tatsuya
目的报道金属支架治疗外源性输尿管梗阻的疗效，并探讨预测支架失效的因素。方法对52例恶性输尿管外源性梗阻患者（66例输尿管）行金属支架治疗（磁共振(R)）。中位观察期为118天。结果患者的中位生存时间为210天，6个月时支架通畅率为86.0%，1年时支架通畅率为60.0%。8例（15.4%）患者因支架失效而行肾造口术。双侧输尿管梗阻的闭塞率明显高于单侧输尿管梗阻。术前血清肌酐水平、输尿管阻塞原因（肿瘤压迫、淋巴结转移、腹膜播散）、梗阻部位（输尿管上、中、下段）与支架失效无相关性。结论金属支架在维持血管通畅方面优于常规支架。因此，它们可作为恶性输尿管梗阻的一线治疗。
ObjectivesTo report the treatment outcomes of patients with extrinsic ureteral obstruction treated with metallic stents and to identify the factors predicting stent failure.MethodsA total of 52 patients with extrinsic ureteral obstruction as a result of malignancy (66 ureters) were treated with metallic stents (Resonance((R))) and included in the study. The median observation period was 118days.ResultsThe median survival time of these patients was 210days, and the stent patency rate was 86.0% at 6months and 60.0% at 1year. Eight (15.4%) patients underwent nephrostomy as a result of stent failure. The occlusion rate of bilateral ureteral obstructed cases was significantly higher than that of unilateral cases. There was no correlation between the preoperative serum creatinine level, causes of ureteral occlusions (compression by tumor, lymph node metastasis, peritoneal dissemination), obstructed site (upper, middle, lower ureter) and stent failure.ConclusionsMetallic stents are excellent in maintaining patency compared with the conventional stents. Therefore, they can be used as first-line treatment of malignant ureteral obstructions.