Inhibitory deficits in attention-deficit/hyperactivity disorder are independent of basic processing efficiency and IQ
Inhibitory deficits in attention-deficit/hyperactivity disorder are independent of basic processing efficiency and IQ
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DOI：
10.1007/s00702-007-0828-z
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发表时间：
2008-02-01
影响因子：
3.3
通讯作者：
Sonuga-Barke, E. J. S.
中科院分区：
文献类型：
--
作者：
Bitsakou, P.;Psychogiou, L.;Sonuga-Barke, E. J. S.
背景注意力缺陷多动障碍（ADHD）儿童中有相当一部分在抑制控制测试中表现出缺陷。然而，问题仍然存在（一）这些赤字的程度，在不同的抑制域，（二）他们的关系，以赤字在非执行过程中，（三）他们是否延伸到adjuncence. Methods。77名ADHD儿童和青少年以及50名非ADHD对照者完成了三项抑制性任务、一项简单的两项选择RT任务（2CR）和一项IQ评估。ADHD与所有任务的缺陷中度相关（效应量d=0.5-0.9）。儿童和青少年时期的赤字同样明显。抑制性缺陷与智商无关，虽然大大减少，但在简单反应时间任务的表现被控制后仍然显着。在强调重要的，但有限的，在多动症的抑制缺陷的作用，这些结果是一致的，强调这种情况下的神经心理异质性的最新帐户。
Background. A substantial proportion of children with attention-deficit/hyperactivity disorder (ADHD) show deficits on inhibitory control tests. However, questions remain about (i) the extent of these deficits across different inhibitory domains, (ii) their relationship to deficits in non-executive processes and (iii) whether they extend into adolescence.Methods. Seventy-seven children and adolescents with ADHD and 50 non-ADHD controls completed three inhibitory tasks, a simple two choice RT task (2CR) and an IQ assessment.Results. ADHD was moderately associated with deficits on all tasks (effect sizes d=0.5-0.9). Deficits were equally marked in childhood and adolescence. Inhibitory deficits were not associated with IQ and, although reduced substantially, remained significant after performance on a simple reaction time task was controlled for statistically.Discussion. In highlighting the significant, but limited, role of inhibitory deficits in ADHD, these results are consistent with recent accounts that emphasize the neuropsychological heterogeneity of this condition.