Bonelike apatite formation on ethylene-vinyl alcohol copolymer modified with silane coupling agent and calcium silicate solutions
Bonelike apatite formation on ethylene-vinyl alcohol copolymer modified with silane coupling agent and calcium silicate solutions
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DOI：
10.1016/s0142-9612(02)00581-1
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发表时间：
2003-05-01
期刊：
影响因子：
14
通讯作者：
Nakamura, T
中科院分区：
文献类型：
--
作者：
Oyane, A;Kawashita, M;Nakamura, T
用硅烷偶联剂和硅酸钙溶液处理乙烯-乙烯醇共聚物（EVOH），然后浸泡在离子浓度近似等于人血浆的模拟体液（SBF）中。在SBF中，在2天内在EVOH板和EVOH编织纤维上成功地形成了光滑均匀的骨样磷灰石层。所得磷灰石-EVOH纤维复合材料的部分结构与天然骨的结构相似。如果这种复合材料能够被制成类似于天然骨的三维结构，则所得到的复合材料有望表现出类似于天然骨的力学性能和骨结合能力。因此，它具有作为骨替代品的巨大潜力。(C)2003爱思唯尔科技有限公司。保留所有权利。
An ethylene-vinyl alcohol copolymer (EVOH) was treated with a silane coupling agent and calcium silicate solutions, and then soaked in a simulated body fluid (SBF) with ion concentrations approximately equal to those of human blood plasma. A smooth and uniform bonelike apatite layer was successfully formed on both the EVOH plate and the EVOH-knitted fibers in SBF within 2 days. Part of the structure of the resulting apatite-EVOH fiber composite was similar to that of natural bone. If this kind of composite can be fabricated into a three-dimensional structure similar to natural bone, the resultant composite is expected to exhibit both mechanical properties analogous to those of natural bone and bone-bonding ability. Hence, it has great potential as a bone substitute. (C) 2003 Elsevier Science Ltd. All rights reserved.