BioHMM:: a heterogeneous hidden Markov model for segmenting array CGH data
BioHMM:: a heterogeneous hidden Markov model for segmenting array CGH data
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DOI:
10.1093/bioinformatics/btl089
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发表时间:
2006-05-01
期刊:
影响因子:
5.8
通讯作者:
Tavaré, S
中科院分区:
文献类型:
--
作者:
Marioni, JC;Thorne, NP;Tavaré, S
We have developed a new method (BioHMM) for segmenting array comparative genomic hybridization data into states with the same underlying copy number. By utilizing a heterogeneous hidden Markov model, BioHMM incorporates relevant biological factors (e.g. the distance between adjacent clones) in the segmentation process.