A 12-week commercial web-based weight-loss program for overweight and obese adults: randomized controlled trial comparing basic versus enhanced features.
A 12-week commercial web-based weight-loss program for overweight and obese adults: randomized controlled trial comparing basic versus enhanced features.
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DOI：
10.2196/jmir.1980
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发表时间：
2012-04-25
影响因子：
7.4
通讯作者：
Callister R
中科院分区：
文献类型：
--
作者：
Collins CE;Morgan PJ;Jones P;Fletcher K;Martin J;Aguiar EJ;Lucas A;Neve MJ;Callister R
基于网络的减肥项目的开发和使用正在迅速增加，但它们很少被随机对照试验（rct）评估。有趣的是，大多数尝试减肥的人使用商业上可用的程序，然而商业程序很少被独立或严格地评估。比较标准的商业网络减肥计划（基本版）与该网络计划的增强版（提供额外的个性化电子反馈和提供者联系）与等候名单对照组（对照组）在超重和肥胖成年人的体重结果方面的效果。这项纯粹基于网络的试验使用封闭的在线用户组，是一项评估盲随机对照试验，参与者随机分配到基于社会认知理论的基本或增强的12周基于网络的计划，或对照组，以体重指数（BMI）作为主要结果。我们招募了309名成人（129/309,41.8%男性，BMI平均值32.3,SD 4 kg/m2）， 12周时保留率为84.1%（260/309）。意向治疗分析显示，与对照组相比，两个干预组的BMI均降低（基本组：-0.72,SD 1.1 kg/m2，增强组：-1.0,SD 1.4，对照组：0.15,SD 0.82, P < 0.001），体重显著减轻（基本组：-2.1,SD 3.3 kg，增强组：-3.0,SD 4.1，对照组：0.4,SD 2.3, P < 0.001），腰围发生变化(基本组：-2.0,SD 3.5 cm，增强组：-3.2,SD 4.7，对照组：0.5,SD 3.0；P < 0.001)和腰高比（基础组：-0.01,SD 0.02，增强组：-0.02,SD 0.03，对照组：0.0,SD 0.02, P < 0.001），但基础组与增强组之间无差异。与基本程序相比，个性化电子反馈和联系的增加提供了有限的额外好处。一个基于网络的商业减肥计划可以有效地跨越一系列与体重相关的结果和生活方式行为，并实现临床重要的减肥。虽然提供额外的个性化反馈并没有在12周后促进更大的体重减轻，但优秀的参与者保留对长期结果的影响需要进一步研究。随着时间的推移，需要进一步的研究来确定导致最大治疗效果的程序特征的最佳组合。澳大利亚新西兰临床试验注册中心（ANZCTR）： 12610000197033；http://www.anzctr.org.au/trial_view.aspx?id=335159（由WebCite在http://www.webcitation.org/66Wq0Yb7U存档）
The development and use of Web-based programs for weight loss is increasing rapidly, yet they have rarely been evaluated using randomized controlled trials (RCTs). Interestingly, most people who attempt weight loss use commercially available programs, yet it is very uncommon for commercial programs to be evaluated independently or rigorously. To compare the efficacy of a standard commercial Web-based weight-loss program (basic) versus an enhanced version of this Web program that provided additional personalized e-feedback and contact from the provider (enhanced) versus a wait-list control group (control) on weight outcomes in overweight and obese adults. This purely Web-based trial using a closed online user group was an assessor-blinded RCT with participants randomly allocated to the basic or enhanced 12-week Web-based program, based on social cognitive theory, or the control, with body mass index (BMI) as the primary outcome. We enrolled 309 adults (129/309, 41.8% male, BMI mean 32.3, SD 4 kg/m2) with 84.1% (260/309) retention at 12 weeks. Intention-to-treat analysis showed that both intervention groups reduced their BMI compared with the controls (basic: –0.72, SD 1.1 kg/m2, enhanced: –1.0, SD 1.4, control: 0.15, SD 0.82; P < .001) and lost significant weight (basic: –2.1, SD 3.3 kg, enhanced: –3.0, SD 4.1, control: 0.4, SD 2.3; P < .001) with changes in waist circumference (basic: –2.0, SD 3.5 cm, enhanced: –3.2, SD 4.7, control: 0.5, SD 3.0; P < .001) and waist-to-height ratio (basic: –0.01, SD 0.02, enhanced: –0.02, SD 0.03, control: 0.0, SD 0.02; P < .001), but no differences were observed between the basic and enhanced groups. The addition of personalized e-feedback and contact provided limited additional benefits compared with the basic program. A commercial Web-based weight-loss program can be efficacious across a range of weight-related outcomes and lifestyle behaviors and achieve clinically important weight loss. Although the provision of additional personalized feedback did not facilitate greater weight loss after 12 weeks, the impact of superior participant retention on longer-term outcomes requires further study. Further research is required to determine the optimal mix of program features that lead to the biggest treatment impact over time. Australian New Zealand Clinical Trials Registry (ANZCTR): 12610000197033; http://www.anzctr.org.au/trial_view.aspx?id=335159 (Archived by WebCite at http://www.webcitation.org/66Wq0Yb7U)
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影响因子：
4.9
作者：
Karlsson, J;Persson, LO;Sullivan, M
通讯作者：
Sullivan, M
肥胖样本中的体重控制的互联网：随机对照试验的结果。
影响因子：
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作者：
McConnon, Aine;Kirk, Sara F. L.;Cockroft, Jennie E.;Harvey, Emma L.;Greenwood, Darren C.;Thomas, James D.;Ransley, Joan K.;Bojke, Laura
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Bojke, Laura
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作者：
Neve M;Morgan PJ;Collins CE
通讯作者：
Collins CE
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Morgan, Philip J.;Lubans, David R.;Callister, Robin
通讯作者：
Callister, Robin
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作者：
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