Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates

Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates
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DOI:
10.1039/b510709a
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发表时间:
2005-11-28
影响因子:
4.9
通讯作者:
Caddick, S
Caddick, S
中科院分区:
化学2区
文献类型:
--
作者:
Vallance, P;Bush, HD;Caddick, S

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五氟苯基(PFP)磺酸酯与不同的硝酮反应生成的一系列五氟苯磺酸酯对细菌酶DDAH和ADI具有显著的抑制活性。
A range of pentafluorophenyl (PFP) sulfonate esters derived from the reaction of PFP vinyl sulfonate and various nitrones are shown to have significant inhibitory activity against the bacterial enzymes DDAH and ADI.