Cutaneous and extracutaneous neutrophilic infiltrates (Sweet syndrome) in three patients with Fanconi anemia.
Cutaneous and extracutaneous neutrophilic infiltrates (Sweet syndrome) in three patients with Fanconi anemia.
复制标题
三名范可尼贫血患者的皮肤和皮外中性粒细胞浸润（Sweet 综合征）。
DOI：
10.1016/s0022-3476(89)80649-3
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Andrews,RG
中科院分区：
文献类型：
--
作者：
Baron,F;Sybert,VP;Andrews,RG
介绍了三名同时患有范科尼综合征和斯威特综合征（中性粒细胞性皮肤病）的患者。在这三例病例中，这些无菌性皮肤损伤均对全身皮质类固醇治疗有反应，并且在治疗停止后又复发。斯威特综合征儿童与恶性肿瘤的关联先前已被认识到。在范可尼贫血的癌前阶段尚未有报道。该报告扩大了中性粒细胞性皮肤病的鉴别诊断。患有 Sweet 综合征和贫血的儿童应通过二环氧丁烷细胞遗传学研究检查范可尼贫血
Three patients with coexistent Fanconi syndrome and Sweet syndrome (neutrophilic dermatosis) are presented. These sterile skin lesions responded to systemic corticosteroid therapy in all three cases, and recurred when treatment was discontinued. The association in children of Sweet syndrome with malignancy has previously been recognized; it has not been reported in the premalignant phase of Fanconi anemia. This report expands the differential diagnosis of the neutrophilic dermatoses. Children with Sweet syndrome and anemia should be examined for Fanconi anemia by diepoxybutane cytogenetic studies