No treatment for low‐risk thrombocythaemia:results from a prospective study

No treatment for low‐risk thrombocythaemia:results from a prospective study
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低危血小板增多症无法治疗:一项前瞻性研究的结果

DOI:
10.1046/j.1365-2141.1998.01021.x
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发表时间:
1998
影响因子:
6.5
通讯作者:
T. Barbui
T. Barbui
中科院分区:
医学2区
文献类型:
--
作者:
M. Ruggeri;G. Finazzi;A. Tosetto;S. Riva;F. Rodeghiero;T. Barbui

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原发性血小板增多症(ET)是一种慢性骨髓增生性疾病,其特征是发生血栓栓塞事件,特别是在年龄> 60岁或既往有血栓形成史的患者中,和/或在血小板计数极高的患者中发生出血。 在这些患者亚组中,使用细胞减灭治疗在风险/获益比方面是有益的。关于血小板计数<1500 × 109/l的年轻无症状ET患者的血栓形成或出血风险和生存率,只有有限的轶事数据。   因此,这些患者的最佳管理是未知的。
Essential thrombocythaemia (ET) is a chronic myeloproliferative disorder characterized by the occurrence of thromboembolic episodes, particularly in patients aged > 60 years or with a previous history of thrombosis, and/or by haemorrhages in patients with an exceedingly high platelet count. In these subgroups of patients the use of cytoreductive therapy is beneficial in terms of risk/benefit ratio. Only limited anecdotal data are available on the thrombotic or haemorrhagic risk and survival in young asymptomatic ET patients with a platelet count < 1500 × 109/l. Therefore the optimal management of these patients is unknown.
原发性血小板增多症:真性红细胞增多症研究小组的中期报告。
DOI: --
发表时间: 1986
影响因子: 3.6
作者:
Murphy,S;Iland,H;Rosenthal,D;Laszlo,J
通讯作者: Laszlo,J
原发性血小板增多症年轻患者的止血并发症。
DOI: 10.1016/0002-9343(90)90491-u
发表时间: 1990
期刊: The American journal of medicine
影响因子: --
作者:
Mitus,AJ;Barbui,T;Shulman,LN;Rosenthal,DS;Viero,P;Cortelazzo,S;Schafer,AI
通讯作者: Schafer,AI