The effect of changing thyroid function on cyclic affective illness in a human subject.

The effect of changing thyroid function on cyclic affective illness in a human subject.
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改变甲状腺功能对人类周期性情感疾病的影响。

DOI:
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发表时间:
1986
影响因子:
17.7
通讯作者:
P. Whybrow
P. Whybrow
中科院分区:
医学1区
文献类型:
--
作者:
M. Bauer;P. Whybrow

文献摘要

被引文献

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甲状腺功能异常在快速循环双相情感疾病患者中很常见。一些快速周期的女性对甲状腺素有反应,但很少有证据表明甲状腺异常的人对甲状腺治疗有反应。作者报告成功的甲状腺素治疗的男子,其快速周期开始和解决后,他的甲状腺状态的变化。他的情感周期被锂和甲状腺素改变。作者认为,中枢神经系统甲状腺状态可能决定了一些人的临床过程中有一个固定的周期的情感发作。
Thyroid function abnormalities are common in persons with rapid-cycling bipolar affective illness. Some women who cycle rapidly respond to thyroxine, but there is scant evidence that the people who have thyroid abnormalities are the ones who respond to thyroid treatment. The authors report successful thyroxine treatment of a man whose rapid cycling began and resolved after changes in his thyroid status. The period of his affective cycle was altered by both lithium and thyroxine. The authors suggest that CNS thyroid status may determine the clinical course of some persons with a fixed cycle of affective episodes.