Posttraumatic stress symptoms in adult survivors of childhood cancer
Posttraumatic stress symptoms in adult survivors of childhood cancer
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DOI：
10.1002/pbc.20024
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发表时间：
2004-06-01
影响因子：
3.2
通讯作者：
de Haan, RJ
中科院分区：
文献类型：
--
作者：
Langeveld, NE;Grootenhuis, MA;de Haan, RJ
背景。先前的研究表明，创伤后应激障碍（PTSD）存在于儿童癌症幸存者中。当前研究的目的是探索创伤后应激症状的年轻成年儿童癌症幸存者的样本。此外，还研究了人口、医疗和治疗因素对幸存者创伤后应激症状的影响。过程。参与者是500名儿童癌症的长期幸存者。随访时中位年龄为24岁（年龄范围1649岁，47%为女性）。为了评估创伤后应激症状，所有参与者都完成了事件影响量表（IES），这是一种自我报告工具，由入侵和回避两个分量表组成。结果。在这些儿童癌症成年幸存者样本中，有12%的人得分在严重范围内，这表明他们无法应对疾病的影响，需要专业帮助。20%的女性幸存者得分在严重范围内，而男性幸存者的这一比例为6%。线性回归模型显示，女性、失业、教育水平较低、诊断类型和严重的后期影响/健康问题与创伤后应激症状有关。结论。结果表明，尽管报告症状的幸存者比例在一般人群中发现的比例范围内，但相当一部分幸存者报告了创伤后应激症状。这一发现支持了先前报道的结果，即儿童癌症的诊断和治疗可能具有显著的长期影响，这表现在创伤后应激症状上。所调查的因素只能在有限程度上解释创伤后应激症状。进一步的研究探索儿童癌症幸存者创伤后应激症状的细节显然是有必要的。从临床角度来看，卫生保健提供者在随访临床评估时必须注意这些症状。早期识别和治疗创伤后应激障碍症状可以提高儿童癌症幸存者的生活质量。(C) 2004 Wiley-Liss, Inc。
Background. Previous research suggests that posttraurnatic stress disorder (PTSD) is present in survivors of childhood cancer. The aim of the current study was to explore posttraurnatic stress symptoms in a sample of young adult survivors of childhood cancer. In addition, the impact of demographic, medical and treatment factors on survivors' posttraumatic stress symptoms was studied. Procedure. Participants were 500 long-term survivors of childhood cancer. The median age at follow-up was 24 years (age range, 1649 years, 47% female). To assess symptoms of posttraumatic stress, all participants completed the Impact of Event Scale (IES), a self-report instrument consisting of two subscales, intrusion and avoidance. Results. Twelve percent of this sample of adult survivors of childhood cancer had scores in the severe range, indicating they are unable to cope with the impact of their disease and need professional help. Twenty percent of the female survivors had scores in the severe range as compared with 6% of the male survivors. Linear regression models revealed that being female, unemployed, a lower educational level, type of diagnosis and severe late effects/health problems were associated with posttraurnatic stress symptoms. Conclusions. The results indicate that, although the proportion of survivors reporting symptoms is well within the proportions found in the general population, a substantial subset of survivors report symptoms of posttraumatic stress. This finding supports the outcomes reported previously that diagnosis and treatment for childhood cancer may have significant long-term effects, which are manifested in symptoms of posttraurnatic stress. The investigated factors could explain posttraurnatic stress symptoms only to a limited extent. Further research exploring symptoms of posttraumatic stress in childhood cancer survivors in more detail is clearly warranted. From a clinical perspective, health care providers must pay attention to these symptoms during evaluations in the follow-up clinic. Early identification and treatment of PTSD symptoms can enhance the quality of life for survivors of childhood cancer. (C) 2004 Wiley-Liss, Inc.