Trends in the Diagnosis and Treatment of Ectopic Pregnancy in the United States
Trends in the Diagnosis and Treatment of Ectopic Pregnancy in the United States
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DOI：
10.1097/aog.0b013e3181d0c328
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发表时间：
2010-03-01
影响因子：
7.2
通讯作者：
Kent, Charlotte K.
中科院分区：
文献类型：
--
作者：
Hoover, Karen W.;Tao, Guoyu;Kent, Charlotte K.
目的：估计在美国异位妊娠的诊断和治疗率的趋势。S.商业保健计划，以及2002至2007年按5岁年龄组和按区域分列的15-44岁女孩和妇女宫外孕率和发病率的估计时间趋势。我们还估计了手术治疗的病例比例的时间趋势，无论是通过腹腔镜或剖腹手术，或药物与methotrexate.Results：我们确定了11,989异位妊娠在2002年至2007年期间。在6年的研究期间，怀孕女孩和15-44岁妇女的异位妊娠总发生率为0.64%。我们没有观察到5岁年龄组或地理区域异位妊娠率的趋势。异位妊娠率随着年龄的增长而增加; 15-19岁的女孩和妇女为0.3%，35-44岁的妇女为1.0%。甲氨蝶呤治疗从2002年的11.1%上升到2007年的35.1%（P
OBJECTIVE: To estimate trends in the rates of diagnosis and treatment of ectopic pregnancy in the United States.METHODS: We analyzed data from a large administrative claims database of more than 200 U. S. commercial health plans, and estimated time trends in the rate and incidence of ectopic pregnancy among girls and women aged 15-44 years by 5-year age groups and by region from 2002 to 2007. We also estimated time trends in the proportion of cases that were treated surgically, either by laparoscopy or laparotomy, or medically with methotrexate.RESULTS: We identified 11,989 ectopic pregnancies during the period from 2002 to 2007. The overall rate of ectopic pregnancy among pregnant girls and women aged 15-44 years during the 6-year study period was 0.64%. We did not observe a trend in the rate of ectopic pregnancy by 5-year age group or by geographic region. The ectopic pregnancy rate increased with age; it was 0.3% among girls and women aged 15-19 years and 1.0% among women aged 35-44 years. Methotrexate treatment increased from 11.1% in 2002 to 35.1% in 2007 (P