Effects of Cholesterol‐Fat Diets on Pigeons Susceptible and Resistant to Atherosclerosis
Effects of Cholesterol‐Fat Diets on Pigeons Susceptible and Resistant to Atherosclerosis
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胆固醇脂肪日粮对易患和抗动脉粥样硬化的鸽子的影响
DOI：
10.1161/01.res.9.1.106
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发表时间：
1961
影响因子：
20.1
通讯作者：
H. Lofland
中科院分区：
文献类型：
--
作者：
T. B. Clarkson;H. Lofland
与对这种疾病有抵抗力的鸽子相比，用胆固醇脂肪食物喂养易患自发性动脉粥样硬化的鸽子明显更容易导致动脉粥样硬化。一种中间易感性的鸽子被发现对高胆固醇-高脂肪饮食的反应是中间的。三个品种的血清胆固醇水平相似。白卡内奥鸽子的病变伴随着结缔组织增生，而自动交配的国王和赛马的鸽子仅仅发展为“纯粹的动脉粥样硬化”或“脂肪条纹”。
Cholesterol-fat diets are markedly more atherogenic when fed to a strain of pigeons susceptible to spontaneous atherosclerosis, as compared to a strain resistant to the disease. A breed of pigeons intermediate in susceptibility was found to be intermediate in their response to a high cholesterol-high fat diet. Serum cholesterol levels were similar among the three breeds. The White Carneau pigeons developed lesions complicated by connective tissue proliferation while the Autosexing Kings and Racing Homers developed merely “pure atheroma” or “fatty streaks.”