Approaches to catalyst discovery. New carbon-heteroatom and carbon-carbon bond formation
Approaches to catalyst discovery. New carbon-heteroatom and carbon-carbon bond formation
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DOI：
10.1351/pac199971081417
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发表时间：
1999-08-01
影响因子：
1.8
通讯作者：
Hartwig, JF
中科院分区：
文献类型：
--
作者：
Hartwig, JF
报道了钯催化芳基卤化物生成芳香胺、芳基醚和α-芳基羰基化合物的研究。这些研究的范围从合成方法到详细的机理分析，再到人们可以用来筛选催化共价键形成的新方法。通过对反应机理的理解，改进了芳基醚的生成方法和室温胺化化学。
Studies on the palladium-catalyzed formation of aryl amines, aryl ethers and a-aryl carbonyl compounds from aryl halides are reported. These studies range from synthetic methodology, to detailed mechanistic analysis, to new methods one can use to screen for catalytic covalent bond formation. Improved methods for formation of aryl ethers and room temperature amination chemistry have resulted from a mechanistic understanding of the reaction.