MutS2 Family Protein from Pyrococcus furiosus
MutS2 Family Protein from Pyrococcus furiosus
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DOI：
10.1007/s00284-001-0025-5
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发表时间：
2002-03
影响因子：
2.6
通讯作者：
R. Vijayvargia;I. Biswas
中科院分区：
文献类型：
--
作者：
R. Vijayvargia;I. Biswas
强烈火球菌MutS2蛋白已被克隆并过表达。初步表征表明，PfuMutS2 具有热稳定 ATP 酶活性和热稳定非特异性 DNA 结合活性。然而，PfuMutS2 不具有任何可检测到的错配特异性 DNA 结合活性。这是 MutS2 家族蛋白的首次体外表征。
MutS2 protein ofPyrococcus furiosushas been cloned and over-expressed. Initial characterization reveals that PfuMutS2 possesses a thermostable ATPase activity and a thermostable, nonspecific DNA binding activity. However, PfuMutS2 does not have any detectable mismatch-specific DNA binding activity. It is the first in vitro characterization of an MutS2 family protein.