Manometric Changes to the Lower Esophageal Sphincter After Magnetic Sphincter Augmentation in Patients With Chronic Gastroesophageal Reflux Disease

Manometric Changes to the Lower Esophageal Sphincter After Magnetic Sphincter Augmentation in Patients With Chronic Gastroesophageal Reflux Disease
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DOI:
10.1097/sla.0000000000001935
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发表时间:
2017-07-01
期刊:
影响因子:
9
通讯作者:
Aye, Ralph W.
Aye, Ralph W.
中科院分区:
医学1区
文献类型:
--
作者:
Warren, Heather F.;Louie, Brian E.;Aye, Ralph W.

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目的:评价磁性括约肌增强术(MSA)对食管下括约肌(LES)的测压变化、功能和影响。背景:在胃食管交界处植入MSA已被证明是治疗胃食管反流病的安全有效的方法,但其对LES的影响尚未阐明。方法:回顾性病例对照研究(n = 121)评价MSA后测压变化。纳入标准包括通过食管pH值异常研究(体重指数)确诊胃食管反流病
Objective: To evaluate the manometric changes, function, and impact of magnetic sphincter augmentation (MSA) on the lower esophageal sphincter (LES).Background: Implantation of a MSA around the gastroesophageal junction has been shown to be a safe and effective therapy for gastroesophageal reflux disease, but its effect on the LES has not been elucidated.Methods: Retrospective case control study (n = 121) evaluating manometric changes after MSA. Inclusion criteria consisted of a confirmed diagnosis of gastroesophageal reflux disease by an abnormal esophageal pH study (body mass index