Short-channel functional near-infrared spectroscopy regressions improve when source-detector separation is reduced
Short-channel functional near-infrared spectroscopy regressions improve when source-detector separation is reduced
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DOI：
10.1117/1.nph.1.1.015002
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发表时间：
2014-07-01
期刊：
影响因子：
5.3
通讯作者：
Berger, Andrew J.
中科院分区：
文献类型：
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作者：
Goodwin, James R.;Gaudet, Chantel R.;Berger, Andrew J.
在人脑血流动力学的功能性近红外光谱 (fNIRS) 中，专用的表面敏感记录通道可用于回归背景血流动力学并隔离激活特异性反应。为此目的，已经利用了各种各样的源-检测器分离。在这里，我们报告了报告范围的两个极端值（13 毫米和 6 毫米）之间回归性能的直接比较。使用具有 13 毫米对角线的标准商用源探测器网格，对 9 名成年人进行了视觉刺激反应（闪烁的径向棋盘）测量，其中放置了三个额外的探测器光纤，以在某些位置提供 6 毫米通道。当处理 NIRS 记录（总共 17 次试验）时，6 毫米回归通道的对比度噪声比显着高于 13 毫米回归通道。这一优势可能部分归因于 13 毫米通道对大脑活动的非预期感知。我们建议考虑较短的距离，以最佳地去除来自成人大脑的 NIRS 信号中的表面血流动力学。 (C) 作者。
In functional near-infrared spectroscopy (fNIRS) of human cerebral hemodynamics, dedicated surface-sensitive recording channels are useful for regressing out background hemodynamics and isolating activation-specific responses. A wide variety of source-detector separations have been utilized for this purpose. Here, we report a direct comparison of regression performance between two extremes of the reported range, 13 and 6 mm. Measurements of visual stimulation response (flickering radial checkerboard) were obtained from nine adults using a standard commercial source-detector grid with 13-mm diagonals, into which three extra detector fibers were placed to provide 6-mm channels at certain locations. When the NIRS recordings (17 total trials) were processed, the contrast-to-noise ratio was significantly higher with 6-mm regression channels than with 13 mm. The advantage could be due in part to the undesired sensing of brain activity by the 13-mm channels. We suggest that shorter distances be considered for optimal removal of superficial hemodynamics in NIRS signals from the adult brain. (C) The Authors.