Current status of mammalian and human models for predicting drug photosensitivity.

Current status of mammalian and human models for predicting drug photosensitivity.
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预测药物光敏性的哺乳动物和人类模型的现状。

DOI:
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发表时间:
1981
影响因子:
6.5
通讯作者:
L. Harber
L. Harber
中科院分区:
医学1区
文献类型:
--
作者:
L. Harber

文献摘要

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本文综述了小型哺乳动物药物光敏反应实验模型的研究进展。本研究的目标是确定光敏性对人类危害的实用且具有较高预测价值的测试。已经使用的各种动物模型系统相对于这些目标进行评价。
The status of efforts to develop experimental models for drug photosensitivity reactions in small mammals is reviewed. Tests which are practical and also have a high predictive value in determining photosensitivity hazards to man are the goal of this research. The various animal model systems which have been used are evaluated with respect to these goals.