Shear and compression rheology of Langmuir monolayers of natural ceramides: solid character and plasticity.
Shear and compression rheology of Langmuir monolayers of natural ceramides: solid character and plasticity.
复制标题
天然神经酰胺朗缪尔单层的剪切和压缩流变学：固体特性和可塑性。
作者：
I. López;Elisa R Catapano;Gabriel Espinosa;L. R. Arriaga;D. Langevin;F. Monroy
目前的工作解决了神经酰胺层膜弹性的基本问题，特别关注塑性状态。使用振荡表面流变学在线性和超越线性状态下研究鸡蛋-神经酰胺朗缪尔单层的压缩和剪切粘弹性。在室温下测量了高压缩模量和剪切模量——这是固体行为的清晰特征。当变形大于每毫米 1 时，鸡蛋-神经酰胺单层表现出塑性特征，其特征是储能模量降低，随后出现流体脂质典型的粘性状态。随着应力增加到屈服点以上，这种行为伴随着损耗模量的显着降低。结果允许将神经酰胺单层明确分类为能够经历塑性变形的二维固体，与典型的流体脂质单层不同。这些不寻常的特征可能会对生物膜中富含神经酰胺的位置的机械行为产生影响。
The present work addresses the fundamental question of membrane elasticity of ceramide layers with a special focus on the plastic regime. The compression and shear viscoelasticity of egg-ceramide Langmuir monolayers were investigated using oscillatory surface rheology in the linear regime and beyond. High compression and shear moduli were measured at room temperature-a clear signature for a solid behavior. At deformations larger than one per mill, egg-ceramide monolayers display plastic features characterized by a decrease of the storage modulus followed by a viscous regime typical of fluid lipids. This behavior is accompanied by a marked decrease of the loss modulus with increasing stress above a yield point. The results permit to univocally classify ceramide monolayers as 2D solids able to undergo plastic deformations, at the difference of typical fluid lipid monolayers. These unusual features are likely to have consequences in the mechanical behavior of ceramide-rich emplacements in biological membranes.
DOI：
10.1073/pnas.84.12.4089
发表时间：
1987-06-01
影响因子：
11.1
作者：
MACDONALD, RC;SIMON, SA
通讯作者：
SIMON, SA
影响因子：
3.4
作者：
Rawicz, W;Olbrich, KC;Evans, E
通讯作者：
Evans, E
影响因子：
56.9
作者：
Bhalla, US;Iyengar, R
通讯作者：
Iyengar, R